Narayan Raja R, Eckardt Mark A, Wang Bonnie O, Fong Zhi Ven, Thompson Christopher C, Wang Jiping
Division of Surgical Oncology, Department of Surgery, Loma Linda University, Loma Linda, CA, USA.
Division of Surgical Oncology, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Ann Surg Oncol. 2025 Sep;32(9):6805-6806. doi: 10.1245/s10434-025-17280-2. Epub 2025 May 20.
Ampullary stenosis can be a late complication of Roux-en-Y gastric bypass (RYGB) causing biliary dyskinesia from ampullary sphincter hypertension (Heetun et al. in Eur J Gastroenterol Hepatol 23:327-333, 2011). Endoscopic management has limited efficacy with Roux anatomy. Thus, pancreatoduodenectomy (PD) may be performed (Wisneski et al. in HPB 22:1496-1503, 2020). In select cases, the morbidity of PD could be avoided using a transduodenal sphincteroplasty.In this report, the case of a patient with ampullary stenosis after RYGB is described. After multiple endoscopic attempts failed to produce durable symptom relief, operative intervention was considered. Choledocho-duodenostomy was deemed technically feasible, but because this patient had preoperative imaging showing that the patient's pancreatic duct communicated independently from the common bile duct (CBD) with the duodenum, robot-assisted transduodenal sphincteroplasty was the selected approach. With this procedure, an extended Kocher maneuver is required for adequate exposure. The lateral duodenal wall is anchored to the falciform ligament using a 2-0 absorbable stitch for retraction. A longitudinal duodenotomy is created along the duodenal wall opposite the major papilla. An 8-Fr catheter inserted through the ampulla into the CBD serves as a probe. Sphincterotomy is performed with electrocautery at the 11 o'clock position, dividing the ampullary sphincter until the CBD wall separates from the duodenal mucosa. A duct-to-mucosa anastomosis is performed using a 5-0 absorbable suture over the 8-Fr catheter, which is left in place: two stitches retracted from the superior CBD facilitate exposure. The duodenotomy is closed transversely with a 3-0 locking absorbable suture in two layers, and a leak test is performed.The patient began oral intake the day after surgery. An upper GI showed no leak on postoperative day 2, and thus the patient was discharged home receiving a liquid diet on postoperative day 3.
壶腹狭窄可能是Roux-en-Y胃旁路术(RYGB)的晚期并发症,由壶腹括约肌高血压导致胆道运动障碍(Heetun等人,《欧洲胃肠病学与肝脏病学杂志》23:327 - 333,2011年)。内镜治疗在Roux解剖结构中疗效有限。因此,可能需要进行胰十二指肠切除术(PD)(Wisneski等人,《HPB》22:1496 - 1503,2020年)。在某些情况下,使用经十二指肠括约肌成形术可避免PD的并发症。在本报告中,描述了一例RYGB术后壶腹狭窄患者的病例。经过多次内镜尝试未能持久缓解症状后,考虑进行手术干预。胆总管十二指肠吻合术在技术上被认为可行,但由于该患者术前影像学显示其胰管与胆总管(CBD)分别与十二指肠相通,因此选择了机器人辅助经十二指肠括约肌成形术。采用该手术时,需要进行扩大的Kocher手法以充分暴露。使用2 - 0可吸收缝线将十二指肠外侧壁固定于镰状韧带以进行牵拉。在十二指肠壁上与主乳头相对处做一纵向十二指肠切口。将一根8F导管经壶腹插入CBD作为探针。在11点位置用电灼进行括约肌切开术,切开壶腹括约肌直至CBD壁与十二指肠黏膜分离。在留置的8F导管上使用5 - 0可吸收缝线进行导管与黏膜吻合:从CBD上方牵拉的两针缝线便于暴露。十二指肠切口用3 - 0锁定可吸收缝线分两层横向缝合,并进行渗漏试验。患者术后第一天开始经口进食。术后第2天上消化道造影显示无渗漏,因此患者在术后第3天出院,接受流食。