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在因脑积水接受脑室腹腔分流术的患者中使用聚-4-羟基丁酸单丝补片预防腹侧疝

Prevention of Abdominal Ventral Hernia Using a Poly-4-Hydroxybutyrate Monofilament Mesh in Patients Undergoing Ventriculoperitoneal Shunt Placement for Hydrocephalus.

作者信息

Christodoulidis Grigorios, Georgakopoulou Vasiliki E, Gatos Charalabos, Baxevanidou Kyriaki, Koumarelas Konstantinos-Eleftherios, Fotakopoulos George

机构信息

Department of Surgery, General University Hospital of Larissa, Larissa, GRC.

Department of Pathophysiology, Laiko General Hospital, Athens, GRC.

出版信息

Cureus. 2025 Apr 21;17(4):e82753. doi: 10.7759/cureus.82753. eCollection 2025 Apr.

Abstract

Background The study aimed to evaluate the efficacy of poly-4-hydroxybutyrate (P4HB) monofilament mesh in preventing abdominal ventral hernia and reducing shunt revisions due to catheter migration in patients undergoing ventriculoperitoneal (VP) shunt surgery for hydrocephalus. Methods This retrospective, single-center study included patients who underwent VP shunt surgery for hydrocephalus between 2017 and 2022. Patients were divided into two groups: Group A (no mesh placement) and Group B (mesh placement using P4HB monofilament mesh for hernia prevention). Data were collected and analyzed to assess the outcomes of hernia prevention and shunt revision rates in both groups. Results Among the 46 patients analyzed, Group B (mesh placement) showed a lower incidence of hernia formation and fewer shunt revisions compared to Group A. BMI and recurrence interval were identified as key predictors of shunt revision, with thresholds of 24.05 kg/m² and 17 months demonstrating high sensitivity and specificity. Conclusions The use of P4HB monofilament mesh in VP shunt surgery effectively reduces hernia formation and shunt revisions. Incorporating this mesh into surgical practice may improve outcomes for patients with hydrocephalus.

摘要

背景 本研究旨在评估聚-4-羟基丁酸酯(P4HB)单丝补片在预防脑室腹腔(VP)分流术治疗脑积水患者的腹侧疝以及减少因导管移位导致的分流管翻修方面的疗效。方法 这项回顾性单中心研究纳入了2017年至2022年间接受VP分流术治疗脑积水的患者。患者分为两组:A组(未放置补片)和B组(使用P4HB单丝补片预防疝)。收集并分析数据以评估两组预防疝的结果和分流管翻修率。结果 在分析的46例患者中,与A组相比,B组(放置补片)疝形成的发生率更低,分流管翻修次数更少。BMI和复发间隔被确定为分流管翻修的关键预测因素,阈值分别为24.05kg/m²和17个月,显示出高敏感性和特异性。结论 在VP分流术中使用P4HB单丝补片可有效减少疝形成和分流管翻修。将这种补片纳入手术实践可能会改善脑积水患者的治疗效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/82ba/12095966/21077dd28953/cureus-0017-00000082753-i01.jpg

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