Wurtz Paul J, Pearman Joseph, Bush Kelvin N V
Department of Medicine, San Antonio Military Medical Center, Fort Sam Houston, Texas, USA.
Division of Cardiology, San Antonio Military Medical Center, Fort Sam Houston, Texas, USA.
JACC Case Rep. 2025 May 21;30(11):103365. doi: 10.1016/j.jaccas.2025.103365. Epub 2025 Apr 23.
Antiarrhythmic drugs commonly used in atrial fibrillation management are associated with variable clinical responses and proarrhythmic properties.
A 53-year-old woman presented with a wide-complex tachycardia. Electrocardiogram after amiodarone administration revealed a flecainide-induced atrial flutter with 1:1 AV conduction and pacemaker interrogation revealed undersensing of presenting ventricular rates at 230 beats/min.
Flecainide therapy has been well-described to organize AF into AFL that is predisposed to 1:1 AV conduction. This case underscores a concerning limitation in the detection of potentially life-threatening arrhythmias with some nominal pacemaker devices.
用于心房颤动管理的抗心律失常药物具有不同的临床反应和促心律失常特性。
一名53岁女性出现宽QRS波心动过速。给予胺碘酮后心电图显示氟卡尼诱发的心房扑动伴1:1房室传导,起搏器程控显示对当时230次/分的心室率感知不足。
氟卡尼治疗已被充分描述为可将房颤组织化为易于出现1:1房室传导的房扑。该病例凸显了一些标称起搏器装置在检测潜在危及生命的心律失常方面存在的令人担忧的局限性。