Weitzenblum E, Krieger J, Kopferschmitt-Kubler M C
Bull Eur Physiopathol Respir. 1985 Jul-Aug;21(4):389-91.
This study describes the case of a 58 year old man who presented with an episode of acute respiratory failure and right heart decompensation. After recovery from the acute illness, hypoxaemia, hypercapnia and pulmonary arterial hypertension remained, the causes of which were not known. There was no airway obstruction, only a moderate restrictive ventilatory defect, a little weight increase and a unilateral diaphragmatic paralysis. Obstructive sleep apnoea was finally suspected and confirmed by sleep recording. The obstructive sleep apnoea probably explained the respiratory insufficiency and the pulmonary hypertension. Loss of weight was associated with the disappearance of hypercapnia and pulmonary hypertension. As a result of this study, the value of sleep recording is emphasized. When respiratory failure or pulmonary hypertension seem unexplained, think of obstructive sleep apnoea.
本研究描述了一名58岁男性患者的病例,该患者出现急性呼吸衰竭和右心代偿失调。在急性疾病康复后,低氧血症、高碳酸血症和肺动脉高压仍然存在,但其病因不明。不存在气道阻塞,仅有中度限制性通气功能障碍、体重略有增加和单侧膈肌麻痹。最终怀疑存在阻塞性睡眠呼吸暂停,并通过睡眠记录得以证实。阻塞性睡眠呼吸暂停可能解释了呼吸功能不全和肺动脉高压。体重减轻与高碳酸血症和肺动脉高压的消失相关。通过本研究,强调了睡眠记录的价值。当呼吸衰竭或肺动脉高压似乎无法解释时,应考虑阻塞性睡眠呼吸暂停。