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一名5岁儿童血友病B的偶然诊断:病例报告

Incidental Diagnosis of Christmas Disease in a 5-year-old Child: A Case Report.

作者信息

Gaviappa Dhananjaya, Shetty Ashmitha K, Jeniffer Nancy, Ramu Somashekar Ankanahaali, Sharma Surabhi, Narayanan Roopa

机构信息

Department of Pediatric and Preventive Dentistry, Faculty of Dental Sciences, Ramaiah University of Applied Sciences, Bengaluru, Karnataka, India.

Department of Pediatrics, Ramaiah Medical College and Hospital, Bengaluru, Karnataka, India.

出版信息

Int J Clin Pediatr Dent. 2025 Feb;18(2):235-238. doi: 10.5005/jp-journals-10005-3048. Epub 2025 Mar 20.

Abstract

CASE DESCRIPTION

A 5-year-old boy presented with bleeding gums following a fall from the swing. Initial treatment at a private clinic involved clot removal and gauze application. Despite no prior history of abnormal bleeding, the child experienced delayed and continuous bleeding, prompting further evaluation. Blood tests revealed normal prothrombin time (PT) but abnormal activated partial thromboplastin time (APTT), indicating a coagulation disorder. Vitamin K was administered, but profuse bleeding recurred, leading to hospital admission. Further tests confirmed a diagnosis of mild hemophilia B with low factor IX levels. The patient received fresh frozen plasma (FFP) transfusion, which stopped the bleeding. Follow-up showed a clean injury site after intervention.

CONCLUSION AND CLINICAL SIGNIFICANCE

This case underscores the need for high suspicion, thorough investigation, and prompt management in bleeding disorders, especially since patients may be unaware of their condition until a bleeding episode occurs.

HOW TO CITE THIS ARTICLE

Gaviappa D, Shetty AK, Jeniffer N, Incidental Diagnosis of Christmas Disease in a 5-year-old Child: A Case Report. Int J Clin Pediatr Dent 2025;18(2):235-238.

摘要

病例描述

一名5岁男孩从秋千上摔下后出现牙龈出血。在一家私人诊所的初步治疗包括清除血块和敷用纱布。尽管该患儿既往无异常出血史,但仍出现延迟性持续出血,遂进行进一步评估。血液检查显示凝血酶原时间(PT)正常,但活化部分凝血活酶时间(APTT)异常,提示存在凝血障碍。给予维生素K治疗,但仍反复出现大量出血,导致患儿住院。进一步检查确诊为轻度乙型血友病,因子IX水平较低。患者接受了新鲜冰冻血浆(FFP)输血,出血得以停止。随访显示干预后伤口部位清洁。

结论及临床意义

该病例强调了对出血性疾病需高度怀疑、全面检查及及时处理的必要性,尤其是因为患者在出血发作前可能并未意识到自己的病情。

如何引用本文

加维亚帕 D、谢蒂 AK、詹妮弗 N,《一名五岁儿童血友病乙的偶然诊断:病例报告》。《国际临床儿科牙科学杂志》2025年;18(2):235 - 238。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de66/12099231/7648e7291375/ijcpd-18-2-235-g001.jpg

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