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社会联系与轻度认知障碍之间的关联:一项针对印度农村老年人群的病例对照研究。

Association between social connectedness and mild cognitive impairment: A case-control study in aging rural Indians.

作者信息

Rai Pooja, Sundarakumar Jonas S

机构信息

Centre for Brain Research, Indian Institute of Science, Bangalore, India.

出版信息

J Alzheimers Dis Rep. 2025 May 25;9:25424823251336115. doi: 10.1177/25424823251336115. eCollection 2025 Jan-Dec.

Abstract

There is a scarcity of evidence on the association between social connectedness and cognitive impairment in the rural Indian population. This cross-sectional study included rural Indians aged 45+ years (n = 5805) from an ongoing aging cohort, the CBR-SANSCOG study. Based on Clinical Dementia Rating (CDR), participants were classified into cognitively normal (CN, CDR = 0) and mild cognitive impairment (MCI, CDR = 0.5). Social networks, assessed across three dimensions (network diversity, size, and embeddedness), were compared between the two groups, adjusting for potential confounders. Individuals with MCI had significantly lower mean scores across all three social network dimensions than CN individuals.

摘要

关于印度农村人口社会联系与认知障碍之间的关联,证据匮乏。这项横断面研究纳入了来自正在进行的老龄化队列研究CBR-SANSCOG研究中的5805名45岁及以上的印度农村居民。根据临床痴呆评定量表(CDR),参与者被分为认知正常(CN,CDR = 0)和轻度认知障碍(MCI,CDR = 0.5)两组。在调整潜在混杂因素后,对两组在社会网络的三个维度(网络多样性、规模和嵌入性)上进行了比较。与认知正常个体相比,轻度认知障碍个体在所有三个社会网络维度上的平均得分均显著更低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ee7/12104604/362e05f6b42e/10.1177_25424823251336115-fig1.jpg

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