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阵发性室上性心动过速对妊娠结局的影响。

Impact of Paroxysmal Supraventricular Tachycardia on Pregnancy Outcomes.

作者信息

Ardehali Arya, Kiess Marla, Rychel Valerie, Barlow Amanda, Oakes Jennifer, Deyell Marc, Grewal Jasmine

机构信息

Division of Cardiology, University of British Columbia, St Paul's Hospital, Vancouver, Canada.

Department of Obstetrics and Gynecology, University of British Columbia, St Paul's Hospital, Vancouver, Canada.

出版信息

CJC Open. 2025 Jan 11;7(4):441-448. doi: 10.1016/j.cjco.2025.01.008. eCollection 2025 Apr.

Abstract

BACKGROUND

Paroxysmal supraventricular tachycardia (PSVT) is one of the most common arrhythmias in pregnant women. However, studies investigating the risk of PSVT in pregnancy are lacking. In pregnancy, we aimed to determine the (1) proportion of women presenting with new-onset PSVT, (2) impact of prior PSVT history on episode severity and management, and (3) rate of adverse maternal and fetal or neonatal outcomes associated with PSVT.

METHODS

Retrospective case-control study: 77 consecutive pregnancies in 75 women referred to the St Paul's Hospital Cardiac Obstetrics Clinic (2010-2022) with a history or new presentation of PSVT. Maternal obstetric and fetal or neonatal adverse outcomes were compared to a healthy control group.

RESULTS

Sixty-three pregnancies (82%) had a history of PSVT and 14 (18%) were new-onset in pregnancy. Sixty-eight percent of those with PSVT history had recurrence in pregnancy. Women with a recent history of PSVT within 5 years of pregnancy were more likely to experience recurrence than women with a remote history (81% vs 31%, < 0.001). This group also experienced more frequent PSVT during pregnancy and increased rates of chemical cardioversion (38% vs 13%,  = 0.05). There were similar rates of adverse obstetric (8% vs 2%,  = 0.24) and fetal or neonatal outcomes (17% vs 19%,  = 0.72) between the PSVT group and controls.

CONCLUSIONS

PSVT events were safely managed in pregnancy with similar obstetric and fetal or neonatal outcomes as controls. However, recurrence of PSVT during pregnancy is frequent and leads to management complexities among those with a history, reinforcing the need for pre-pregnancy counselling and catheter ablation for definitive management.

摘要

背景

阵发性室上性心动过速(PSVT)是孕妇最常见的心律失常之一。然而,缺乏关于孕期PSVT风险的研究。在孕期,我们旨在确定:(1)新发PSVT的女性比例;(2)既往PSVT病史对发作严重程度及治疗的影响;(3)与PSVT相关的孕产妇及胎儿或新生儿不良结局发生率。

方法

回顾性病例对照研究:连续纳入圣保罗医院心脏产科门诊(2010 - 2022年)的75名女性的77次妊娠,这些女性有PSVT病史或新发PSVT。将孕产妇产科及胎儿或新生儿不良结局与健康对照组进行比较。

结果

63次妊娠(82%)有PSVT病史,14次妊娠(18%)为孕期新发。有PSVT病史的患者中,68%在孕期复发。妊娠5年内近期有PSVT病史的女性比远期有病史的女性更易复发(81%对31%,<0.001)。该组在孕期PSVT发作更频繁,化学复律率更高(38%对13%,P = 0.05)。PSVT组与对照组的不良产科结局发生率(8%对2%,P = 0.24)及胎儿或新生儿结局发生率(17%对19%,P = 0.72)相似。

结论

孕期PSVT事件得到安全管理,产科及胎儿或新生儿结局与对照组相似。然而,PSVT在孕期频繁复发,给有病史者带来治疗复杂性,这凸显了孕前咨询及导管消融进行确定性治疗的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee9f/12105748/a746ef164829/gr1.jpg

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