Taguchi Kazumi, Hamamoto Shuzo, Kawase Kengo, Unno Rei, Okada Atsushi, Mizuno Kentaro, Maruyama Tetsuji, Yasui Takahiro
Department of Nephro-Urology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Department of Urology, Nagoya City University East Medical Center, Nagoya, Japan.
Int J Urol. 2025 Sep;32(9):1203-1209. doi: 10.1111/iju.70127. Epub 2025 May 28.
Ureteral strictures, a common complication of ureteral stone treatment, pose substantial challenges. These conditions often necessitate robot-assisted ureteral reconstruction (RUR), a procedure complicated by difficulty in identifying and mobilizing adhesive ureters. This study evaluated the effectiveness of a ureteral illuminating catheter (IRIS U-kit) in enhancing visualization and securing adhesive ureters during RUR.
This retrospective cohort study included 24 patients who underwent RUR for stone-related ureteral strictures at two academic centers in Japan between April 2022 and June 2024. The patients were divided into two groups: those with the IRIS catheter and those with conventional indocyanine green (ICG) and near-infrared fluorescence imaging. The primary endpoint was a stent-free status with preserved renal function. Secondary outcomes included surgical time and postoperative recovery metrics.
Each group included 12 patients during the study period. The IRIS catheter group demonstrated a 54% reduction in ureter securing time (38.0 vs. 82.5 min, p = 0.001) and a 33-min shorter console duration (144.0 vs. 177.0 min, p = 0.005) than the ICG group. All patients in both groups achieved a stent-free status by 6-7 weeks postoperatively, with no significant differences in serum creatinine levels or estimated glomerular filtration rates between the preoperative and postoperative periods. Additionally, both groups showed significant improvement in hydronephrosis, with moderate to severe grades decreasing from 41.7% preoperatively to 8.3% postoperatively.
The IRIS catheter significantly enhanced the efficiency of RUR by improving the visualization of adhesive ureters without compromising the ability to observe other anatomical structures.
输尿管狭窄是输尿管结石治疗的常见并发症,带来了重大挑战。这些情况通常需要机器人辅助输尿管重建术(RUR),而该手术因难以识别和游离粘连的输尿管而变得复杂。本研究评估了输尿管照明导管(IRIS U-kit)在RUR期间增强可视化和固定粘连输尿管方面的有效性。
这项回顾性队列研究纳入了2022年4月至2024年6月期间在日本两个学术中心因结石相关输尿管狭窄接受RUR的24例患者。患者分为两组:使用IRIS导管的患者和使用传统吲哚菁绿(ICG)及近红外荧光成像的患者。主要终点是无支架且肾功能保留的状态。次要结果包括手术时间和术后恢复指标。
研究期间每组各有12例患者。与ICG组相比,IRIS导管组的输尿管固定时间减少了54%(38.0分钟对82.5分钟,p = 0.001),控制台操作时间缩短了33分钟(144.0分钟对177.0分钟,p = 0.005)。两组所有患者术后6 - 7周均达到无支架状态,术前和术后血清肌酐水平或估计肾小球滤过率无显著差异。此外,两组肾积水均有显著改善,中重度等级从术前的41.7%降至术后的8.3%。
IRIS导管通过改善粘连输尿管的可视化显著提高了RUR的效率,同时不影响观察其他解剖结构的能力。