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蜂窝织炎性胃炎作为急性白血病的首发表现:一例报告

Phlegmonous Gastritis as the First Presentation of Acute Leukemia: A Case Report.

作者信息

Alkubaisi Mohammed A, Mohammed Nader K, Ibrahim Ibrahim S, Rashid Hamza I

机构信息

Medicine, Peterborough City Hospital, Peterborough, GBR.

Gastroenterology, Peterborough City Hospital, Peterborough, GBR.

出版信息

Cureus. 2025 Apr 28;17(4):e83156. doi: 10.7759/cureus.83156. eCollection 2025 Apr.

DOI:10.7759/cureus.83156
PMID:40443637
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12120320/
Abstract

Phlegmonous gastritis (PG) is a serious and severe suppurative gastric infection. Diagnosis is delayed due to its uncommon and non-specific clinical presentation. This led to a high mortality rate; however, early treatment with broad-spectrum antibiotics can reduce mortality and complications. We describe a case of a 56-year-old patient who presented with severe abdominal pain, vomiting, and pyrexia. Blood tests showed pancytopenia, and she was newly diagnosed with acute myeloid leukemia (AML) on this admission. Her computed tomography (CT) and endoscopic evaluation showed thickening and swelling of the gastric wall consistent with PG. She responded well to conservative treatment, and she is on regular follow-up as an outpatient. This case highlights the importance of suspecting PG in severe abdominal pain and neutropenia. This will reduce the complications, mortality, and requirement for surgical intervention.

摘要

蜂窝织炎性胃炎(PG)是一种严重的化脓性胃部感染。由于其临床表现不常见且不具有特异性,诊断往往会延迟。这导致了较高的死亡率;然而,早期使用广谱抗生素治疗可降低死亡率和并发症。我们描述了一例56岁患者,该患者出现严重腹痛、呕吐和发热。血液检查显示全血细胞减少,此次入院时新诊断为急性髓系白血病(AML)。她的计算机断层扫描(CT)和内镜检查显示胃壁增厚和肿胀,符合蜂窝织炎性胃炎。她对保守治疗反应良好,目前作为门诊患者定期随访。该病例强调了在严重腹痛和中性粒细胞减少时怀疑蜂窝织炎性胃炎的重要性。这将减少并发症、死亡率以及手术干预的需求。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c729/12120320/6d5c6cf459c4/cureus-0017-00000083156-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c729/12120320/71b3be14da37/cureus-0017-00000083156-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c729/12120320/9c3e758ebdf7/cureus-0017-00000083156-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c729/12120320/cfa69e853d25/cureus-0017-00000083156-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c729/12120320/40909b7ca739/cureus-0017-00000083156-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c729/12120320/6d5c6cf459c4/cureus-0017-00000083156-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c729/12120320/71b3be14da37/cureus-0017-00000083156-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c729/12120320/9c3e758ebdf7/cureus-0017-00000083156-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c729/12120320/cfa69e853d25/cureus-0017-00000083156-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c729/12120320/40909b7ca739/cureus-0017-00000083156-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c729/12120320/6d5c6cf459c4/cureus-0017-00000083156-i05.jpg

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本文引用的文献

1
Phlegmonous gastritis: Review of the pathophysiology.蜂窝织炎性胃炎:病理生理学综述
Am J Med Sci. 2024 Apr;367(4):274-277. doi: 10.1016/j.amjms.2024.01.019. Epub 2024 Jan 27.
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A Rare Case of Phlegmonous Gastritis in a Previously Healthy Male: A Case Report.一例既往健康男性的蜂窝织炎性胃炎罕见病例:病例报告
Cureus. 2023 Feb 15;15(2):e35013. doi: 10.7759/cureus.35013. eCollection 2023 Feb.
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Phlegmonous gastritis: a case series.蜂窝织炎性胃炎:病例系列。
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Phlegmonous Gastritis: A Case Report of Successful Early Antibiotic Treatment.蜂窝织炎性胃炎:早期抗生素治疗成功的病例报告
Cureus. 2021 Feb 15;13(2):e13359. doi: 10.7759/cureus.13359.
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Successful Antimicrobial Treatment of Phlegmonous Gastritis: A Case Report and Literature Review.蜂窝织炎性胃炎的成功抗菌治疗:病例报告及文献综述
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