Georgoulis George, Joud Anthony, Sindou Marc
Department of Neurosurgery, General Hospital of Athens "G. Gennimatas", Athens, Greece.
Department of Pediatric Neurosurgery Centre Hospitalo-Universitaire de Nancy, Nancy, France.
Adv Tech Stand Neurosurg. 2025;51:139-163. doi: 10.1007/978-3-031-86441-4_11.
To optimize the efficacy of dorsal rhizotomy (DRh) in treating spasticity associated with cerebral palsy, the authors advocate for individual access (intradurally) to all roots from L2 to S2. The initial step involves the use of electrical stimulation of the ventral root (VR) to confirm their anatomical identity and determine their corresponding myotomal territory of innervation, which is known to exhibit interindividual variability (anatomical mapping). The primary objective is then to employ dorsal root (DR) stimulation to assess their respective reflexive excitability levels (physiological testing). To mitigate the risk of spine destabilization, access is gained through enlarged interlaminar openings while preserving the spinous processes and interspinous ligaments. This approach is termed Keyhole Interlaminar Dorsal rhizotomy (KIDr). Intradural access to the roots is achieved at their preforaminal zone, through a L1-L2 opening for the L2 and L3 roots, L3-L4 opening for the L4 and L5 roots, and L5-S1 opening for the L5 and S1 roots. Under microsurgical visualization, at each exposed root level, the VR is stimulated to verify its myotomal distribution, and the DR is stimulated to estimate the segmental reflexive excitability using Fasano's grading system, allowing for the adjustment of the number of rootlets per root to be severed. In our practice, indications are primarily based on the Gross Motor Function Classification System (GMFCS): for individuals classified as levels III and IV, the goal is to enhance functional status and prevent or halt deformities; for those at level V and quadriplegic patients, the aim is to improve comfort, reduce pain, facilitate care, and alleviate upper limb disability through the "distant effects" often observed following lumbo-sacral rhizotomy. The timing of surgery is determined not only by age-related locomotor development but also by the plateau or deterioration of the Gross Motor Function Measure (GMFM) curve despite intensive rehabilitation efforts. As with all specialized centers, the surgical schedule is established in collaboration with a multidisciplinary team and documented in a comprehensive chart, alongside the Gain Attainment project.
为优化背根切断术(DRh)治疗脑瘫相关痉挛的疗效,作者主张经硬膜内单独处理从L2至S2的所有神经根。第一步是利用腹侧神经根(VR)电刺激来确认其解剖学特征,并确定其相应的神经支配肌节区域,已知该区域存在个体差异(解剖图谱绘制)。然后主要目标是采用背根(DR)刺激来评估其各自的反射兴奋性水平(生理测试)。为降低脊柱失稳风险,通过扩大椎板间隙进入,同时保留棘突和棘间韧带。这种方法称为锁孔椎板间背根切断术(KIDr)。在神经根的椎间孔前区经硬膜内进入神经根,通过L1-L2间隙处理L2和L3神经根,L3-L4间隙处理L4和L5神经根,L5-S1间隙处理L5和S1神经根。在显微手术视野下,在每个暴露的神经根水平,刺激VR以验证其肌节分布,并使用法萨诺分级系统刺激DR以估计节段性反射兴奋性,从而调整每根要切断的神经根丝数量。在我们的实践中,手术指征主要基于粗大运动功能分类系统(GMFCS):对于GMFCS分级为III级和IV级的患者,目标是改善功能状态并预防或阻止畸形;对于V级患者和四肢瘫患者,目的是通过腰骶部背根切断术后常观察到的“远隔效应”来提高舒适度、减轻疼痛、便于护理并减轻上肢残疾。手术时机不仅取决于与年龄相关的运动发育情况,还取决于尽管进行了强化康复治疗但粗大运动功能测量(GMFM)曲线仍处于平台期或恶化的情况。与所有专业中心一样,手术计划是与多学科团队协作制定的,并记录在一份综合图表中,同时还有增益达成项目。