非转移性尤因肉瘤的放射治疗。
Radiotherapy of non-metastatic ewing sarcoma.
作者信息
Prindull G, Jürgens H, Jentsch F, Sauer R, Lasson U
出版信息
J Cancer Res Clin Oncol. 1985;110(2):127-30. doi: 10.1007/BF00402725.
Abstract
Comparing the radiotherapy data of two groups of patients with non-metastatic Ewing sarcoma, we came to the following conclusions: intensive chemotherapy does not substitute for effective radiotherapy. Irradiation fields should be large enough to include the whole affected bone and the entire extra-osseous compartments, exempting only uninvolved epiphyses. Marginal recurrences are a major risk of the shrinking field technique. Single doses per fraction should be high and the total dose raised to the point of maximal irradiation tolerance of normal tissues.
摘要
比较两组非转移性尤因肉瘤患者的放疗数据后，我们得出以下结论：强化化疗不能替代有效的放疗。照射野应足够大，以包括整个受累骨骼和整个骨外间隙，仅不累及未受累的骨骺。边缘复发是缩野技术的主要风险。每次分割的单次剂量应较高，总剂量应提高到正常组织最大耐受照射剂量的程度。
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