特发性纤维硬化症
Idiopathic fibrosclerosis.
作者信息
Brooks M S, Robinson J A
出版信息
J Rheumatol. 1985 Jun;12(3):575-9.
Idiopathic fibrosclerosis (IF) is an acute and chronic inflammatory cellular infiltration of tissue associated with varying amounts of fibrosis. Clinical prototypes of IF include retroperitoneal fibrosis, mediastinal fibrosis and Reidel's struma of the thyroid. IF has been associated with numerous other diseases in the literature including systemic lupus erythematosus, scleroderma, polyarteritis nodosa and reactions to several drugs, especially, methysergide and several antihypertensive. However, no clear etiologic factor for either the inflammatory component or the fibrosis has been found. We present 2 cases of IF that exemplify the protean nature of the disease and its potential response to immunosuppressive therapy.
特发性纤维硬化症（IF）是一种急性和慢性炎症性细胞浸润组织的疾病，伴有不同程度的纤维化。IF的临床典型病例包括腹膜后纤维化、纵隔纤维化和甲状腺的里德耳氏甲状腺肿。在文献中，IF还与许多其他疾病有关，包括系统性红斑狼疮、硬皮病、结节性多动脉炎以及对多种药物的反应，尤其是麦角新碱和几种抗高血压药物。然而，尚未发现炎症成分或纤维化的明确病因。我们报告2例IF病例，以说明该疾病的多变性质及其对免疫抑制治疗的潜在反应。
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