Wang Jou-Hua, Yao Shu-Hsin, Wang Ting-Ming, Lin Chii-Jeng, Lin Chang-Hao, Chen Chun-Ho
Department of Orthopaedic Surgery, National Cheng Kung University Hospital, Tainan, Taiwan.
Department of Biomedical Engineering, National Cheng Kung University, Tainan, Taiwan.
BMC Musculoskelet Disord. 2025 Jun 3;26(1):551. doi: 10.1186/s12891-025-08740-7.
This study evaluated the effectiveness of integrating Graf method into the universal neonatal screening program for detecting developmental dysplasia of the hip (DDH) in Taiwanese population.
A total of 4,667 neonates screened between May 2014 and November 2019 were enrolled in this study. Hip ultrasound scans were performed three days after birth, and hips were classified based on their morphology and stability. The incidence rates of early diagnosis, late diagnosis, and surgical interventions for DDH were assessed. Risk factors and treatment measures for DDH were documented.
During the initial examination, 95.95% of hips were classified as Graf type I, while a small proportion were classified as types IIa, IIc (stable/unstable), or III. By the second examination at 4 weeks, all type IIa hips had matured to type I. A total of 35 hips (0.37%) were diagnosed with DDH and treated with a Pavlik harness before 12 weeks, resulting in an early diagnosis rate of 0.37%, with no cases of late diagnosis reported. The incidence of DDH-related surgeries was 0.04%. Multivariable logistic regression identified female sex (OR = 2.41, 95% CI: 1.05-5.52, p = 0.038) and breech presentation (OR = 6.54, 95% CI: 2.22-19.32, p < 0.001) as significant risk factors for DDH.
Universal neonatal ultrasound screening using the Graf method is simple and beneficial in the early detection and intervention of DDH. Additionally, it significantly reduces the rates of late diagnosis and the need for surgical intervention.
本研究评估了将Graf方法纳入台湾地区新生儿髋关节发育不良(DDH)普遍筛查项目的有效性。
本研究纳入了2014年5月至2019年11月期间筛查的4667例新生儿。出生后三天进行髋关节超声扫描,并根据髋关节的形态和稳定性进行分类。评估DDH的早期诊断、晚期诊断和手术干预的发生率。记录DDH的危险因素和治疗措施。
在初次检查时,95.95%的髋关节被分类为Graf I型,而一小部分被分类为IIa、IIc(稳定/不稳定)或III型。在4周时的第二次检查中,所有IIa型髋关节均已成熟为I型。共有35例髋关节(0.37%)在12周前被诊断为DDH并采用Pavlik吊带治疗,早期诊断率为0.37%,无晚期诊断病例报告。DDH相关手术的发生率为0.04%。多变量逻辑回归确定女性(OR = 2.41,95%CI:1.05 - 5.52,p = 0.038)和臀位(OR = 6.54,95%CI:2.22 - 19.32,p < 0.001)是DDH的显著危险因素。
使用Graf方法进行新生儿普遍超声筛查在DDH的早期检测和干预中简单且有益。此外,它显著降低了晚期诊断率和手术干预的需求。