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Hidden Preeclampsia Leading to Placental Abruption and Disseminated Intravascular Coagulation.隐匿性子痫前期导致胎盘早剥和弥散性血管内凝血。
Cureus. 2025 May 4;17(5):e83469. doi: 10.7759/cureus.83469. eCollection 2025 May.
2
The comparison of placental abruption coupled with and without preeclampsia and/or intrauterine growth restriction in singleton pregnancies.比较胎盘早剥合并与不合并子痫前期和/或宫内生长受限的单胎妊娠。
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本文引用的文献

1
DIC in Pregnancy - Pathophysiology, Clinical Characteristics, Diagnostic Scores, and Treatments.妊娠期弥散性血管内凝血——病理生理学、临床特征、诊断评分及治疗
J Blood Med. 2022 Jan 6;13:21-44. doi: 10.2147/JBM.S273047. eCollection 2022.
2
Uterine tachysystole: a survey of CAOG members suggests persistent ambiguity.子宫收缩过频:一项针对妇产科医师协会成员的调查表明其仍存在定义不明确的问题。
J Matern Fetal Neonatal Med. 2021 Jul;34(14):2369-2374. doi: 10.1080/14767058.2019.1661989. Epub 2019 Sep 11.
3
Acute tocolysis for uterine tachysystole or suspected fetal distress.针对子宫收缩过速或疑似胎儿窘迫的急性宫缩抑制。
Cochrane Database Syst Rev. 2018 Jul 4;7(7):CD009770. doi: 10.1002/14651858.CD009770.pub2.
4
Disseminated intravascular coagulation.弥散性血管内凝血
Crit Care Med. 2007 Sep;35(9):2191-5. doi: 10.1097/01.ccm.0000281468.94108.4b.
5
Single injection of terbutaline in term labor. I. Effect on fetal pH in cases with prolonged bradycardia.足月分娩时单次注射特布他林。I. 对长时间心动过缓病例胎儿pH值的影响。
Am J Obstet Gynecol. 1985 Dec 15;153(8):859-65. doi: 10.1016/0002-9378(85)90690-8.

隐匿性子痫前期导致胎盘早剥和弥散性血管内凝血。

Hidden Preeclampsia Leading to Placental Abruption and Disseminated Intravascular Coagulation.

作者信息

Biju Nivedita, Backer Corinne

机构信息

Obstetrics and Gynecology, A.T. Still University, Saint Louis, USA.

Obstetrics and Gynecology, Mercy Health, Saint Louis, USA.

出版信息

Cureus. 2025 May 4;17(5):e83469. doi: 10.7759/cureus.83469. eCollection 2025 May.

DOI:10.7759/cureus.83469
PMID:40462801
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12133109/
Abstract

Placental abruption is a life-threatening obstetric emergency, often associated with hypertensive disorders such as preeclampsia. This study describes a 28-year-old multiparous woman at 36 weeks and four days of gestation who presented with contractions without any overt signs of preeclampsia. Despite an initial blood pressure of 130/85 mmHg, fetal bradycardia and uterine tachysystole prompted an emergency cesarean section. Intraoperative findings confirmed placental abruption, and postoperative laboratory results revealed significant proteinuria, confirming undiagnosed preeclampsia. Postpartum complications included severe hemorrhage exceeding 2000 mL, progressing to disseminated intravascular coagulation (DIC), which required aggressive resuscitation, a massive transfusion protocol, and intensive care management. This case emphasized the challenge of diagnosing "hidden" preeclampsia, the variability of placental abruption presentations, and the importance of early recognition and intervention. Clinicians should maintain a high index of suspicion for atypical presentations of preeclampsia to mitigate adverse maternal and fetal outcomes.

摘要

胎盘早剥是一种危及生命的产科急症,常与子痫前期等高血压疾病相关。本研究描述了一名28岁经产妇,妊娠36周零4天时出现宫缩,但无明显子痫前期迹象。尽管初始血压为130/85 mmHg,但胎儿心动过缓和子宫收缩过频促使进行急诊剖宫产。术中发现证实为胎盘早剥,术后实验室检查结果显示大量蛋白尿,确诊为未诊断出的子痫前期。产后并发症包括严重出血超过2000 mL,进展为弥散性血管内凝血(DIC),这需要积极复苏、大规模输血方案和重症监护管理。该病例强调了诊断“隐匿性”子痫前期的挑战、胎盘早剥表现的变异性以及早期识别和干预的重要性。临床医生应对子痫前期的非典型表现保持高度怀疑,以减轻母婴不良结局。