Mehta Chirag, Shin Abraham, Osorio Brian, DePolo Daniel, Vargas Irene, Hao Emily, Khan Ali, Chandragiri Sahas, Shringi Sandipan, McLean Diaz Paige O, Potter Nicholas S, Godding Mark, Poppas Athena, Kataria Rachna, Saad Marwan, Hyder Omar, Sodha Neel R, Abbott J Dawn, Vallabhajosyula Saraschandra
Department of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America.
Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America.
Am Heart J Plus. 2025 May 1;55:100549. doi: 10.1016/j.ahjo.2025.100549. eCollection 2025 Jul.
Cardiogenic shock (CS) is a syndrome of low cardiac output leading to systemic hypoperfusion. The mainstay of management involves optimizing preload, afterload, and contractility to restore central hemodynamics. However, CS is frequently complicated by non-cardiac organ failure, for which there is limited guidance. Herein, we review the pathophysiology, assessment, and management of respiratory, renal, hepatic, and neurological failure in the context of CS. This review is intended to provide an evidence-based framework for the management of extracardiac sequelae for the patients in the cardiac and medical intensive care unit.
心源性休克(CS)是一种由于心输出量降低导致全身灌注不足的综合征。治疗的主要方法包括优化前负荷、后负荷和心肌收缩力以恢复中心血流动力学。然而,CS常并发非心脏器官功能衰竭,对此的指导有限。在此,我们回顾了CS背景下呼吸、肾脏、肝脏和神经功能衰竭的病理生理学、评估和管理。本综述旨在为心脏和内科重症监护病房患者的心脏外后遗症管理提供一个基于证据的框架。