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评估100例神经功能受损患者腹腔镜胃底折叠术围手术期结局的相关影响因素:一项多中心回顾性联合研究

Evaluating the relevant factors affecting the perioperative outcomes of laparoscopic fundoplication in 100 neurologically impaired patients: a multicenter retrospective joint study.

作者信息

Koga Yoshinori, Sugita Koshiro, Hashizume Naoki, Masui Daisuke, Nakame Kazuhiko, Onishi Shun, Torikai Motofumi, Ieiri Satoshi, Kaji Tatsuru

机构信息

Department of Pediatric Surgery, Kurume University School of Medicine, 67 Asahi-Machi, Kurume, 830-0011, Japan.

Department of Pediatric Surgery, Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area, Research and Education Assembly, Kagoshima University, Kagoshima, Japan.

出版信息

Surg Today. 2025 Jun 4. doi: 10.1007/s00595-025-03067-1.

DOI:10.1007/s00595-025-03067-1
PMID:40468003
Abstract

BACKGROUND

Postural features (e.g. scoliosis) make laparoscopic fundoplication more difficult in neurologically impaired patients (NIPs) than in non-NIPs [please check this carefully]. We therefore clarified the relevant factors associated with perioperative outcomes of NIPs.

METHODS

NIPs who underwent laparoscopic Nissen fundoplication were enrolled. We classified the patients according to age into < 18- and ≥ 18-year-old groups and evaluated the factors associated with perioperative outcomes. The endpoints were patient characteristics, acid-reflux index, operative time, blood loss, postoperative outcomes, and Endoscopic Surgical Skill Qualification System (ESSQS) certification.

RESULTS

One hundred and one patients underwent laparoscopic fundoplication. Blood loss and operative time were significantly higher in the ≥ 18-year-old group than in the < 18-year-old group. A multivariate regression analysis revealed that no factors were significantly associated with blood loss. However, a significant association was observed between the procedure performed by the ESSQS-certified pediatric surgeon and the operative time. In terms of postoperative outcomes, the length of hospital stay after operations performed or supervised by ESSQS-certified pediatric surgeons was significantly shorter than that after operations performed by pediatric surgeons without ESSQS certification.

CONCLUSION

The involvement of pediatric surgeons with ESSQS certification was significantly associated with perioperative outcomes in NIPs during laparoscopic fundoplication, whereas physical characteristics and GER were not.

LEVELS OF EVIDENCE

Level III, case-control study.

摘要

背景

与非神经功能受损患者相比,神经功能受损患者(NIPs)的姿势特征(如脊柱侧弯)使腹腔镜胃底折叠术的难度增加[请仔细核对这点]。因此,我们阐明了与NIPs围手术期结局相关的因素。

方法

纳入接受腹腔镜Nissen胃底折叠术的NIPs。我们根据年龄将患者分为<18岁组和≥18岁组,并评估与围手术期结局相关的因素。终点指标包括患者特征、酸反流指数、手术时间、失血量、术后结局以及内镜手术技能资格认证系统(ESSQS)认证。

结果

101例患者接受了腹腔镜胃底折叠术。≥18岁组的失血量和手术时间显著高于<18岁组。多因素回归分析显示,没有因素与失血量显著相关。然而,观察到ESSQS认证的儿科外科医生进行的手术与手术时间之间存在显著关联。在术后结局方面,ESSQS认证的儿科外科医生实施或监督的手术后住院时间显著短于未获得ESSQS认证的儿科外科医生实施的手术后住院时间。

结论

在腹腔镜胃底折叠术中,ESSQS认证的儿科外科医生的参与与NIPs的围手术期结局显著相关,而身体特征和胃食管反流则不然。

证据级别

III级,病例对照研究。

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本文引用的文献

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J Gastrointest Surg. 2023 Dec;27(12):2718-2723. doi: 10.1007/s11605-023-05877-5. Epub 2023 Nov 6.
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How many cases do instructor class pediatric surgeons need to experience to be an independent operator in performing advanced endoscopic surgery? A nationwide survey to establish an ideal curriculum for pediatric endoscopic surgery in Japan.指导级小儿外科医师需要完成多少例手术才能独立进行高级内镜手术?日本小儿内镜外科学理想课程的全国性调查。
Pediatr Surg Int. 2023 Sep 9;39(1):271. doi: 10.1007/s00383-023-05550-7.
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The usefulness of the endoscopic surgical skill qualification system in laparoscopic right hemicolectomy: a single-center, retrospective analysis with propensity score matching.
内镜手术技能资格认证系统在腹腔镜右半结肠切除术的应用:单中心回顾性分析及倾向评分匹配研究。
Langenbecks Arch Surg. 2023 Jan 16;408(1):33. doi: 10.1007/s00423-023-02810-x.
4
Clinical impact of Endoscopic Surgical Skill Qualification System (ESSQS) by Japan Society for Endoscopic Surgery (JSES) for laparoscopic distal gastrectomy and low anterior resection based on the National Clinical Database (NCD) registry.日本内镜外科学会(JSES)的内镜手术技能资格认定系统(ESSQS)基于国家临床数据库(NCD)登记,对腹腔镜远端胃切除术和低位前切除术的临床影响。
Ann Gastroenterol Surg. 2020 Aug 31;4(6):721-734. doi: 10.1002/ags3.12384. eCollection 2020 Nov.
5
Impact of the Endoscopic Surgical Skill Qualification System on the safety of laparoscopic gastrectomy for gastric cancer.内镜外科技能资格认证系统对胃癌腹腔镜胃切除术安全性的影响。
Surg Endosc. 2021 Nov;35(11):6089-6100. doi: 10.1007/s00464-020-08102-5. Epub 2020 Oct 22.
6
Does the "Endoscopic Surgical Skill Qualification System" Reduce Serious Intraoperative Complications in the Field of Pediatric Surgery?“内镜手术技能资质认证体系”是否降低了小儿外科学领域的严重术中并发症?
J Laparoendosc Adv Surg Tech A. 2020 Dec;30(12):1282-1285. doi: 10.1089/lap.2020.0309. Epub 2020 Aug 26.
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Gastroesophageal reflux in children with neurological impairment: a systematic review and meta-analysis.神经功能障碍儿童的胃食管反流:一项系统评价和荟萃分析。
Pediatr Surg Int. 2018 Nov;34(11):1139-1149. doi: 10.1007/s00383-018-4335-0. Epub 2018 Aug 13.
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Gastroesophageal reflux disease: the results of videolaparoscopic fundoplication at five years after surgery.
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