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种植体周围炎非重建性手术治疗的疗效:美国牙周病学会/骨科学会关于翻瓣术与骨手术程序的系统评价和荟萃分析

Efficacy of Nonreconstructive Surgical Treatment of Peri-implantitis: An AAP/AO Systematic Review and Meta-analysis of Access Flap Versus Osseous Surgery Procedures.

作者信息

Saleh Muhammad H A, Misch Craig, Alrmali Abdusalam, Neiva Rodrigo

出版信息

Int J Oral Maxillofac Implants. 2025 Jun 6(4):73-90. doi: 10.11607/jomi.2025suppl3.

Abstract

PURPOSE

To estimate and compare the effect of two different nonreconstructive surgical techniques for treating periimplantitis.

MATERIALS AND METHODS

An electronic search was performed in PubMed, Web of Science, Embase, Scopus, Ovid Medline, and the Cochrane Library of the Cochrane Collaboration (CENTRAL) for articles published until September 2023. Studies evaluating surgical nonreconstructive techniques for the treatment of peri-implantitis were included. The primary outcomes were changes in pocket probing depth (PPD) and bleeding on probing (BoP). Secondary outcomes included marginal bone levels (MBLs) and plaque index (PI) changes. Meta-analysis and meta-regression were performed. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach was used to determine the quality of evidence. Results were grouped according to their treatment techniques: (1) flap surgeries and (2) osseous resective surgeries (nonreconstructive).

RESULTS

The final stage of screening included 15 clinical trials. At 12 months, the flap group had a mean PPD reduction of 1.27 mm (95% CI: 0.67-1.87; I2 = 95.9%), and the osseous resective group had a PPD reduction of 1.88 mm (95% CI: 1.39-2.37; I2 = 97.1%), showing no significant differences (P = .119). Regarding BoP, there were no significant differences between the two techniques at 3, 6, or 12 months. For MBL, at 12 months, the flap group showed less bone loss than the osseous resective group (mean difference = 0.73 mm; P < .001).

CONCLUSIONS

Both nonreconstructive surgical interventions were effective in managing peri-implantitis. Moderate-quality evidence suggested that flap surgeries may provide a slight advantage in maintaining MBLs compared to osseous resective surgery.

摘要

目的

评估和比较两种不同的非重建性手术技术治疗种植体周围炎的效果。

材料与方法

在PubMed、科学网、Embase、Scopus、Ovid Medline以及Cochrane协作网图书馆(CENTRAL)中进行电子检索,检索截至2023年9月发表的文章。纳入评估手术非重建性技术治疗种植体周围炎的研究。主要结局指标为探诊深度(PPD)变化和探诊出血(BoP)情况。次要结局指标包括边缘骨水平(MBL)和菌斑指数(PI)变化。进行荟萃分析和荟萃回归。采用推荐分级的评估、制定和评价(GRADE)方法确定证据质量。结果根据治疗技术分组:(1)翻瓣手术和(2)骨切除术(非重建性)。

结果

筛选的最后阶段纳入了15项临床试验。在12个月时,翻瓣组PPD平均降低1.27mm(95%CI:0.67 - 1.87;I² = 95.9%),骨切除组PPD降低1.88mm(95%CI:1.39 - 2.37;I² = 97.1%),差异无统计学意义(P = 0.119)。关于BoP,在3、6或12个月时,两种技术之间无显著差异。对于MBL,在12个月时,翻瓣组骨吸收少于骨切除组(平均差异 = 0.73mm;P < 0.001)。

结论

两种非重建性手术干预在治疗种植体周围炎方面均有效。中等质量的证据表明,与骨切除术相比,翻瓣手术在维持MBL方面可能具有轻微优势。

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