Ngumbau Nancy M, Kimonge Damaris, Dettinger Julia C, Abuna Felix, Odhiambo Ben, Gómez Laurén, Wagner Anjuli D, Marwa Mary M, Watoyi Salphine, Nzove Emmaculate, Pintye Jillian, Baeten Jared M, Kinuthia John, John-Stewart Grace, Mugo Cyrus
Research & Programs, Kenyatta National Hospital, Nairobi, Kenya.
Department of Global Health, University of Washington, Seattle, Washington, United States of America.
PLOS Glob Public Health. 2025 Jun 6;5(6):e0004353. doi: 10.1371/journal.pgph.0004353. eCollection 2025.
There are limited data on uptake of postpartum family planning (FP), particularly in high HIV prevalence settings. We assessed the timing of modern postpartum FP initiation and the cofactors of earlier uptake using longitudinal data from a clinical trial conducted in Kenya to assess two models of PrEP delivery among pregnant and postpartum women (NCT#03070600). Time to uptake of modern postpartum FP was estimated using survival analysis methods, and Cox proportional hazard models were used to determine cofactors of earlier uptake of modern postpartum FP. Among 4,191 women, median age was 24 years, 17% were aged 15-19 years, 88% were in a steady relationship, 50% intended to be pregnant and 75% were multigravida. The median time to resumption of sex was 8 weeks postpartum versus 24 weeks for uptake of postpartum FP. At 6 weeks postpartum, 42% of women had resumed sex, versus 12% who took up FP; at 14 weeks, 79% versus 38%; at 6 months, 88% versus 59%; and at 9 months, 91% versus 80%, respectively. Injectables and implants were the most common FP methods. Approximately 3.3% of all women became pregnant during the 9-month postpartum period. Being older and having ≤4children was associated with earlier uptake of modern postpartum FP. Women with lower education, primigravida, low social support, history of miscarriage/stillbirth, without a partner at enrolment, not residing with their partners, not receiving financial support from their partner and whose youngest child at enrolment was < 2years had later uptake of postpartum FP. Women who were ambivalent about their immediate previous pregnancy took up postpartum FP later than those who intended to be pregnant. Our findings underscore the importance of addressing the individual, interpersonal, social and obstetric factors associated with timeliness of postpartum FP uptake during the development and delivery of postpartum FP interventions, particularly in high HIV prevalence settings.
关于产后计划生育(FP)的采用情况,尤其是在艾滋病毒高流行地区,相关数据有限。我们利用在肯尼亚进行的一项临床试验的纵向数据,评估了现代产后FP开始的时间以及更早采用的相关因素,该试验旨在评估两种针对孕妇和产后妇女的暴露前预防(PrEP)模式(NCT#03070600)。使用生存分析方法估计采用现代产后FP的时间,并使用Cox比例风险模型确定更早采用现代产后FP的相关因素。在4191名妇女中,中位年龄为24岁,17%的年龄在15 - 19岁之间,88%处于稳定关系,50%打算怀孕,75%为经产妇。恢复性生活的中位时间是产后8周,而采用产后FP的时间是24周。产后6周时,42%的妇女恢复了性生活,而采用FP的为12%;14周时,分别为79%和38%;6个月时,分别为88%和59%;9个月时,分别为91%和80%。注射剂和植入物是最常见的FP方法。在产后9个月期间,所有妇女中约3.3%怀孕。年龄较大且子女≤4个与更早采用现代产后FP有关。教育程度较低、初产妇、社会支持低、有流产/死产史、入组时没有伴侣、不与伴侣同住、未获得伴侣的经济支持以及入组时最年幼的孩子<2岁的妇女,采用产后FP的时间较晚。对前次妊娠态度矛盾的妇女比打算怀孕的妇女采用产后FP的时间更晚。我们的研究结果强调了在制定和实施产后FP干预措施时,特别是在艾滋病毒高流行地区,解决与产后FP及时采用相关的个人、人际、社会和产科因素的重要性。