Ivanova L G, Kliucheva V V, Blagoveshchenskiĭ V A, Lebedenko G I, Saprykina T P
Zh Mikrobiol Epidemiol Immunobiol. 1977 Feb(2):48-53.
The authors demonstrated an incomplete indentity of Cl. botulinum hemagglutinins of types A and B in the double diffusion reaction in agar gel, and their difference by electrophoretic mobility. Some differences in the interaction of hemagglutinins A and B with human erythrocytes were found by the hemagglutination inhibition method; apparently, of the principal significance in the relization of the reaction of human erythrocyte hemagglutination with hemagglutinins of Cl. botulinum, types A and B, was the OH-group position in the C4 galactose of the mucopolysaccharides of the erythrocyte cell wall. Apart from C4, apparently, for hemagglutinin of types A of significance was the reactive capacity of C1 and C2 galactose atoms, whereas for hemagglutinin of type B--free OH-group in C2 galactose atom.
作者们在琼脂凝胶双扩散反应中证明了A型和B型肉毒杆菌血凝素的不完全同一性，以及它们在电泳迁移率上的差异。通过血凝抑制法发现血凝素A和B与人红细胞相互作用存在一些差异；显然，在A型和B型肉毒杆菌血凝素与人红细胞血凝反应的实现过程中，红细胞细胞壁粘多糖C4半乳糖上的OH基团位置具有主要意义。除了C4外，显然，对于A型血凝素来说，C1和C2半乳糖原子的反应能力具有重要意义，而对于B型血凝素来说，C2半乳糖原子上的游离OH基团具有重要意义。
