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The ABCs of lipid exposure in maintaining neural health.
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Phagocytosis-driven neurodegeneration through opposing roles of an ABC transporter in neurons and phagocytes.
Sci Adv. 2025 Mar 14;11(11):eadr5448. doi: 10.1126/sciadv.adr5448. Epub 2025 Mar 12.
3
Reduced expression of gene in cortex glia causes dopaminergic cell death.
J Parkinsons Dis. 2025 Aug;15(5):957-969. doi: 10.1177/1877718X251349407. Epub 2025 Jun 16.
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Pyruvate kinase deficiency links metabolic perturbations to neurodegeneration and axonal protection.
Mol Metab. 2025 Jun 10;98:102187. doi: 10.1016/j.molmet.2025.102187.
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Structure and Mechanism of Human ABC Transporters.
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本文引用的文献

1
Adipocyte metabolic state regulates glial phagocytic function.
Cell Rep. 2025 May 27;44(5):115704. doi: 10.1016/j.celrep.2025.115704. Epub 2025 May 14.
2
Phagocytosis-driven neurodegeneration through opposing roles of an ABC transporter in neurons and phagocytes.
Sci Adv. 2025 Mar 14;11(11):eadr5448. doi: 10.1126/sciadv.adr5448. Epub 2025 Mar 12.
3
Diet-induced glial insulin resistance impairs the clearance of neuronal debris in Drosophila brain.
PLoS Biol. 2023 Nov 7;21(11):e3002359. doi: 10.1371/journal.pbio.3002359. eCollection 2023 Nov.
4
ABCA1 is an extracellular phospholipid translocase.
Nat Commun. 2022 Aug 16;13(1):4812. doi: 10.1038/s41467-022-32437-3.
5
New insights into the genetic etiology of Alzheimer's disease and related dementias.
Nat Genet. 2022 Apr;54(4):412-436. doi: 10.1038/s41588-022-01024-z. Epub 2022 Apr 4.
6
The Drama of Wallerian Degeneration: The Cast, Crew, and Script.
Annu Rev Genet. 2021 Nov 23;55:93-113. doi: 10.1146/annurev-genet-071819-103917. Epub 2021 Aug 5.
7
Sleep Regulates Glial Plasticity and Expression of the Engulfment Receptor Draper Following Neural Injury.
Curr Biol. 2020 Mar 23;30(6):1092-1101.e3. doi: 10.1016/j.cub.2020.02.057. Epub 2020 Mar 5.
8
Phosphatidylserine recognition and induction of apoptotic cell clearance by Drosophila engulfment receptor Draper.
J Biochem. 2013 May;153(5):483-91. doi: 10.1093/jb/mvt014. Epub 2013 Feb 18.
9
The Drosophila cell corpse engulfment receptor Draper mediates glial clearance of severed axons.
Neuron. 2006 Jun 15;50(6):869-81. doi: 10.1016/j.neuron.2006.04.028.

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