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开窗/分支型血管腔内修复术治疗胸腹主动脉瘤术后再次干预分析

Analysis of postoperative reintervention for thoracoabdominal aortic aneurysm treated with fenestrated/branched endovascular repair.

作者信息

Pan Zhaohui, Fu Dongsheng, Hu Jianhang, Han Yuexue, Liu Zhao

机构信息

Department of Vascular Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.

出版信息

Front Cardiovasc Med. 2025 May 27;12:1530974. doi: 10.3389/fcvm.2025.1530974. eCollection 2025.

Abstract

OBJECTIVE

Fenestrated/branched endovascular repair (F/B EVAR) has emerged as a frontline treatment for complex aortic diseases, yet multiple studies have reported high reintervention rates postoperatively. This study aims to discuss strategies for improving patient prognosis by analyzing the reintervention status following F/B EVAR in a single-center patient cohort.

METHODS

This is a single-center retrospective study that collected clinical data and follow-up information from patients who underwent F/B EVAR for complex thoracoabdominal aortic aneurysms between January 2018 and June 2024. The study investigated risk factors leading to reintervention, the association between reintervention and postoperative complications and mortality, and other related aspects.

RESULTS

A total of 103 patients were included, with 21 patients undergoing a total of 35 reinterventions during the follow-up period. Among these, 19 reintervention events occurred within 12 months after F/B EVAR (19/103, 18.4%). The reintervention group had significantly higher rates of hypertension, prior endovascular surgery, larger maximum aneurysm diameters, longer operative durations, and more postoperative ICU days compared to the non-reintervention group ( < 0.05). Hypertension (OR: 10.239, 95% CI: 0.999-104.916), maximum aneurysm diameter (OR: 1.591, 95% CI: 1.035-2.446), and operative duration (OR: 1.010, 95% CI: 1.004-1.017) were independent risk factors for reintervention. The most common reintervention methods were SMA branch stent implantation (4/35, 11.4%) and embolization of aortic endoleaks (4/35, 11.4%). The primary indication for reintervention was type IIIc endoleak (12/35, 34.3%). Most patients undergoing reintervention were discharged after interventional or open treatment, with 2 deaths post-intervention (2/21, 9.5%), a higher mortality rate than the non-reintervention group (3/82, 3.7%), but the difference was not statistically significant ( = 0.269).

CONCLUSION

Hypertension, maximum aneurysm diameter, and operative duration were independent risk factors for reintervention. Type IIIc endoleak was the primary indication for unplanned postoperative reintervention, and interventional treatment was the most common reintervention method. Early postoperative follow-up is crucial, and personalized follow-up strategies and surgical approach selection are key to improving long-term prognosis.

摘要

目的

开窗/分支型血管腔内修复术(F/B EVAR)已成为复杂主动脉疾病的一线治疗方法,但多项研究报告术后再干预率较高。本研究旨在通过分析单中心患者队列中F/B EVAR术后的再干预情况,探讨改善患者预后的策略。

方法

这是一项单中心回顾性研究,收集了2018年1月至2024年6月期间因复杂胸腹主动脉瘤接受F/B EVAR治疗的患者的临床数据和随访信息。该研究调查了导致再干预的危险因素、再干预与术后并发症及死亡率之间的关联以及其他相关方面。

结果

共纳入103例患者,其中21例患者在随访期间共接受了35次再干预。其中,19次再干预事件发生在F/B EVAR术后12个月内(19/103,18.4%)。与未再干预组相比,再干预组的高血压、既往血管腔内手术史、最大动脉瘤直径更大、手术时间更长以及术后ICU住院天数更多(<0.05)。高血压(OR:10.239,95%CI:0.999 - 104.916)、最大动脉瘤直径(OR:1.591,95%CI:1.035 - 2.446)和手术时间(OR:1.010,95%CI:1.004 - 1.017)是再干预的独立危险因素。最常见的再干预方法是肠系膜上动脉分支支架植入(4/35,11.4%)和主动脉内漏栓塞(4/35,11.4%)。再干预的主要指征是Ⅲc型内漏(12/35,34.3%)。大多数接受再干预的患者在介入或开放治疗后出院,干预后有2例死亡(2/21,9.5%),死亡率高于未再干预组(3/82,3.7%),但差异无统计学意义(=0.269)。

结论

高血压、最大动脉瘤直径和手术时间是再干预的独立危险因素。Ⅲc型内漏是计划外术后再干预的主要指征,介入治疗是最常见的再干预方法。术后早期随访至关重要,个性化的随访策略和手术方式选择是改善长期预后的关键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/658a/12148869/56a796ec2958/fcvm-12-1530974-g001.jpg

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