de Lima Aline Gouvêa, Palma Luiz Felipe, Taveira Andressa, Marcucci Marcelo, Gavini Giulio
School of Dentistry, University of São Paulo, Brazil.
Department of Pathology, Federal University of São Paulo, Brazil.
Natl J Maxillofac Surg. 2025 Jan-Apr;16(1):39-43. doi: 10.4103/njms.njms_118_24. Epub 2025 Apr 28.
The present study aimed to retrospectively investigate whether there is a difference in the occurrence of apical periodontitis (AP) between patients diagnosed with head and neck cancer (HNC) and non-HNC individuals, given the scarcity of studies on the subject.
Medical records from 660 patients diagnosed with HNC and 167 without any diagnosis of malignancy were selected. The radiographs were examined by two experienced examiners, and the images were classified as normal or altered.
281 oncologic patients (comprising 4391 teeth) and 144 non-oncologic patients (comprising 3094 teeth) were evaluated. Radiographic signs of AP were found in 16.19% and 9.02% of teeth in HNC and non-HNC patients, respectively ( < 0.0001). Considering teeth without endodontic treatment, the prevalence of AP was 15.90% in HNC patients and 6.41% in the others ( < 0.0001). However, there was no difference between the groups regarding AP in endodontically treated teeth (25.37% in the HNC group and 30.42% in the non-HNC group; = 0.35).
Within the study's limitations, patients diagnosed with HNC present a higher prevalence of AP compared to non-HNC patients, both in general and concerning endodontically untreated teeth.
鉴于关于该主题的研究较少，本研究旨在回顾性调查诊断为头颈癌（HNC）的患者与非HNC个体之间根尖周炎（AP）的发生率是否存在差异。
选取660例诊断为HNC的患者和167例未诊断出任何恶性肿瘤的患者的病历。由两名经验丰富的检查人员检查X光片，并将图像分类为正常或异常。
对281例肿瘤患者（共4391颗牙齿）和144例非肿瘤患者（共3094颗牙齿）进行了评估。HNC患者和非HNC患者中分别有16.19%和9.02%的牙齿出现AP的影像学征象（<0.0001）。对于未经牙髓治疗的牙齿，HNC患者中AP的患病率为15.90%，其他患者中为6.41%（<0.0001）。然而，在牙髓治疗过的牙齿方面，两组之间的AP发生率没有差异（HNC组为25.37%，非HNC组为30.42%；P=0.35）。
在本研究的局限性范围内，诊断为HNC的患者与非HNC患者相比，AP的患病率总体上更高，在未经牙髓治疗的牙齿方面也是如此。
