Lenz G, Lampl L, Hug J
Anaesthesist. 1985 Aug;34(8):392-5.
Although surgical mortality associated with pheochromocytoma has been markedly reduced in recent years, due to improvements in medical and anesthesiologic management, surgery in patients with unsuspected pheochromocytoma is still accompanied by a high fatality rate. A 20-year-old man without history of hypertension and previously in good health is reported who presented for exploratory thoracotomy and removal of a highly vascular mediastinal tumor. Intraoperatively a pheochromocytoma was suspected. Problems associated with establishing the diagnosis as well as difficulties in treating rapid changes of sympathetic adrenergic activation and hypotension following tumor resection are discussed. Despite the comparative rarety of pheochromocytoma the anaesthesiologist should be aware of unusual clinical manifestations.
尽管近年来与嗜铬细胞瘤相关的手术死亡率由于医学和麻醉管理的改善而显著降低,但未被怀疑患有嗜铬细胞瘤的患者进行手术时,死亡率仍然很高。本文报道了一名20岁男性,无高血压病史,此前身体健康,因进行 exploratory thoracotomy(开胸探查术)并切除一个血管丰富的纵隔肿瘤前来就诊。术中怀疑为嗜铬细胞瘤。文中讨论了与诊断确立相关的问题,以及肿瘤切除后交感肾上腺素能激活快速变化和低血压治疗方面的困难。尽管嗜铬细胞瘤相对罕见,但麻醉医生应意识到其不寻常的临床表现。 (注:原文中“exploratory thoracotomy”直译为“探索性开胸术”,这里意译为“开胸探查术”更符合语境)