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经乳突入路使用羟基磷灰石骨水泥修复上半规管裂

Superior Semicircular Canal Dehiscence Repair With Hydroxyapetite Cement via a Transmastoid Approach.

作者信息

Shah Hemali, Ninan Sen, Shah Rema, Reeder Allison, Kveton John, Schwartz Nofrat

机构信息

Department of Otolaryngology Yale School of Medicine, Yale New Haven Hospital New Haven CT USA.

出版信息

Laryngoscope Investig Otolaryngol. 2025 Jun 14;10(3):e70164. doi: 10.1002/lio2.70164. eCollection 2025 Jun.

Abstract

INTRODUCTION

The aim of this study was to assess the efficacy of superior semicircular canal dehiscence (SSCD) repair via a transmastoid approach using hydroxyapatite bone cement capping.

METHODS

This retrospective case series was carried out at a tertiary referral center. All patients were ≥ 18-years-old diagnosed with SSCD between 2012 and 2022 and underwent a transmastoid approach implementing hydroxyapatite capping. Dehiscence location and size were assessed by reviewing preoperative CT temporal bone scans and correlated to the success rate of surgical repair. The failure rate (lack of symptom resolution and/or persistent dehiscence on postoperative imaging) and/or need for revision surgery were evaluated.

RESULTS

Twenty-two patients (25 ears) were included. Mean age was 50.8 years (SD = 9.9 years) with 50.0% female patients ( = 11). The predominant location of SSCD was determined as apical (76.0%,  = 19), followed by anterior limb (12.0%,  = 3) and posterior limb (12.0%,  = 3). Mean dehiscence size was 2.8 mm (SD = 1.4 mm). Median follow-up time after repair was 9.0 months (interquartile range: 2-36 months). Failure rate was 8.0% ( = 2). Both cases demonstrated persistent SSCD on postoperative imaging; one case had a residual apical dehiscence of 1.6 mm persistent at 4 months, and one had a posterior-apical dehiscence of 2.3 mm persistent at 8 months after surgery.

DISCUSSION

Transmastoid approach for SSCD repair with hydroxyapatite bone cement capping has a relatively low failure and complication rate, alleviating the need for middle fossa approach. To our knowledge, this case series represents the largest for this approach and material combination for SSCD repair, demonstrating that transmastoid repair with bone cement represents a promising approach for effective management of patients with SSCD.

LEVEL OF EVIDENCE

摘要

引言

本研究的目的是评估采用乳突入路并使用羟基磷灰石骨水泥覆盖修复上半规管裂(SSCD)的疗效。

方法

本回顾性病例系列研究在一家三级转诊中心进行。所有患者年龄≥18岁,于2012年至2022年间被诊断为SSCD,并接受了采用羟基磷灰石覆盖的乳突入路手术。通过回顾术前颞骨CT扫描评估裂的位置和大小,并将其与手术修复成功率相关联。评估失败率(术后影像学检查显示症状未缓解和/或裂持续存在)和/或翻修手术的必要性。

结果

纳入22例患者(25耳)。平均年龄为50.8岁(标准差=9.9岁),女性患者占50.0%(n=11)。SSCD的主要位置确定为顶部(76.0%,n=19),其次是前支(12.0%,n=3)和后支(12.0%,n=3)。平均裂大小为2.8毫米(标准差=1.4毫米)。修复后的中位随访时间为9.0个月(四分位间距:2 - 36个月)。失败率为8.0%(n=2)。两例患者术后影像学检查均显示SSCD持续存在;一例患者术后4个月顶部残留1.6毫米的裂持续存在,另一例患者术后8个月后顶部裂2.3毫米持续存在。

讨论

采用乳突入路并使用羟基磷灰石骨水泥覆盖修复SSCD的失败率和并发症率相对较低,减少了对中颅窝入路的需求。据我们所知,该病例系列是这种用于SSCD修复的入路和材料组合的最大病例系列,表明使用骨水泥进行乳突修复是有效治疗SSCD患者的一种有前景的方法。

证据级别

4级。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a28/12166310/30067cd899c3/LIO2-10-e70164-g002.jpg

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