[接受光和声系统刺激的KM品系大鼠癫痫发作易感性水平的变化]

[Changes in the level of seizure readiness of KM strain rats undergoing systematic stimulation by light and sound].

作者信息

Riabinskaia E A, Korotun S Iu, Novozhilova E A

出版信息

Nauchnye Doki Vyss Shkoly Biol Nauki. 1985(8):51-6.

Abstract

A possibility of reflex change in the rats seizure activity level of KM line in which an intensive sound causes epileptiform seizures has been studied. Interrupted light stimulation (non-specific for the given form of seizures) does not cause any seizures. It has been found however that the initial presentations of light stimulation favour the increase of seizure activity level in rats. Prolonged systematic stimulation by an intensive sound or by the light + sound complex cause a gradual drop in the seizure activity level. The light cancellation following a prolonged systematic stimulation by light + + sound causes a short-term rise in the seizure activity level.

摘要

研究了在KM系大鼠中，强烈声音可引发癫痫样发作，其癫痫发作活动水平出现反射性变化的可能性。间断光刺激（对特定形式的癫痫发作无特异性）不会引发任何癫痫发作。然而，已发现光刺激的初始表现有利于大鼠癫痫发作活动水平的升高。长时间通过强烈声音或光+声音组合进行系统性刺激会导致癫痫发作活动水平逐渐下降。在光+声音长时间系统性刺激后取消光刺激会导致癫痫发作活动水平出现短期升高。