Wampola H
Fortschr Med. 1977 May 12;95(18):1240,1242-5.
The therapeutical effect of Defluina was studied in a selective open trial of 50 patients suffering from peripheral arterial occlusive diseases of different stages. All patients were treated with Defluina, 30 drops three times a day during a period of six weeks. Control parameters of 46 patients (18 males, 26 females, mean age of 59.8 +/- 1.7 years) were evaluated. After therapy a significant improvement of all applied parameters was observed. The positive effect of the Defluina-medication on the initial--partly severe--varicose ulcera, with gangrenous alterations, has to be pointed out. After 6 weeks the varicose ulcera were partly closed, at least they showed fresh granulations. During therapy no adverse reactions were registered. All patients estimated Defluina as very well tolerable. The therapeutic effect of Defluina on the carefully investigated group of 46 patients could be estimated in 38 cases with excellent/good, in 7 cases with good/moderate and only in 1 case with moderate.
在一项针对50例不同阶段外周动脉闭塞性疾病患者的选择性开放试验中，研究了去氟那（Defluina）的治疗效果。所有患者均接受去氟那治疗，为期六周，每天三次，每次30滴。对46例患者（18例男性，26例女性，平均年龄59.8±1.7岁）的对照参数进行了评估。治疗后，所有应用参数均有显著改善。必须指出，去氟那药物对最初部分严重的伴有坏疽性改变的静脉曲张性溃疡有积极作用。6周后，静脉曲张性溃疡部分愈合，至少出现了新鲜肉芽组织。治疗期间未记录到不良反应。所有患者均认为去氟那耐受性良好。在46例经过仔细研究的患者中，去氟那的治疗效果在38例中评估为优秀/良好，7例中评估为良好/中等，仅1例中评估为中等。
