一例巨大腘静脉动脉瘤合并肝素诱导的血小板减少症抗体阳性且反复发生急性肺栓塞的手术病例。
A Case of Surgery for a Giant Popliteal Venous Aneurysm Positive for Heparin-Induced Thrombocytopenia Antibodies with Repeated Acute Pulmonary Embolism.
作者信息
Tomita Satoru, Yokawa Koki, Yoshida Kazufumi, Masada Kenta, Inoue Yosuke, Seike Yoshimasa, Matsuda Hitoshi
机构信息
Department of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
出版信息
Ann Vasc Dis. 2025;18(1). doi: 10.3400/avd.cr.25-00031. Epub 2025 Jun 17.
A 56-year-old woman with recurrent acute pulmonary embolism was diagnosed with a left popliteal venous aneurysm (PVA) by venous echocardiography. During anticoagulation therapy with heparin for acute pulmonary embolism, she was found to be positive for heparin-induced thrombocytopenia (HIT) antibodies. Surgery was performed with argatroban for anticoagulation, removal of the thrombus in the PVA, and suturing of the vein. Postoperatively, the popliteal vein showed shrinkage, and no recurrence of thromboembolism was observed. We report a case in which a patient with a PVA positive for HIT antibodies was successfully treated with PVA resection and anticoagulation therapy with argatroban.
一名56岁复发性急性肺栓塞女性患者经静脉超声心动图诊断为左腘静脉瘤（PVA）。在使用肝素进行急性肺栓塞抗凝治疗期间，发现她的肝素诱导的血小板减少症（HIT）抗体呈阳性。采用阿加曲班进行抗凝、切除PVA内血栓并缝合静脉的手术。术后，腘静脉出现萎缩，未观察到血栓栓塞复发。我们报告一例HIT抗体阳性的PVA患者通过PVA切除和阿加曲班抗凝治疗成功治愈的病例。
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