Mathisen Sven R, Berge Simen Tveten
Department of Vascular Surgery, Innlandet Hospital Trust, Hamar, Norway.
Department of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Vasc Health Risk Manag. 2025 Jun 13;21:477-488. doi: 10.2147/VHRM.S513365. eCollection 2025.
The aim of this study was to investigate the early and late outcomes of Open Surgical Conversion (OSC) following the failure of Endovascular Aneurysm Sealing (EVAS) endografts, regarding surgical technique, morbidity and mortality.
A single center retrospective observational cohort of 46 patients undergoing OSC after EVAS failure. Primary endpoints were primary technical procedural success and 30-day mortality. Secondary endpoints were complications and primary prosthesis patency.
Primary technical procedural success was 97.8% (45/46). Elective 30-day mortality for OSC was 10.9% (5/42) and 75% (3/4) for acute OSC procedures. Median survival after OSC was 4.2 years (IQR 1.0, 4.9 years). Four peri-operative and 17 post-operative complications were registered. Major complications included bleeding, myocardial infraction, acute renal failure and splenectomy. Primary prosthesis patency was 82.6% (38/46) at 30-days. At median follow-up of 4.7 years (IQR 3.9, 5.3 years) 69.6% (32/46) of the patients are still alive with patent vascular prostheses.
Open surgical conversion achieved acceptable technical success rate for failed EVAS, with better outcomes in elective versus emergency procedures. Enhanced surveillance with timely interventions before rupture and careful patient selection through multidisciplinary evaluation are essential for optimizing surgical outcomes.
本研究旨在探讨血管内动脉瘤封堵术(EVAS)失败后开放性手术转换(OSC)的早期和晚期结果,包括手术技术、发病率和死亡率。
一项单中心回顾性观察队列研究,纳入46例EVAS失败后接受OSC的患者。主要终点为主要技术操作成功率和30天死亡率。次要终点为并发症和原发性假体通畅率。
主要技术操作成功率为97.8%(45/46)。OSC的择期30天死亡率为10.9%(5/42),急性OSC手术的死亡率为75%(3/4)。OSC后的中位生存期为4.2年(四分位间距1.0,4.9年)。记录到4例围手术期并发症和17例术后并发症。主要并发症包括出血、心肌梗死、急性肾衰竭和脾切除术。30天时原发性假体通畅率为82.6%(38/46)。在中位随访4.7年(四分位间距3.9,5.3年)时,69.6%(32/46)的患者存活,血管假体通畅。
开放性手术转换对于失败的EVAS取得了可接受的技术成功率,择期手术的结果优于急诊手术。在破裂前加强监测并及时干预,通过多学科评估仔细选择患者,对于优化手术结果至关重要。