人工智能在类风湿关节炎、轴性脊柱关节炎和银屑病关节炎管理中的当前应用、可能性及挑战。
Current application, possibilities, and challenges of artificial intelligence in the management of rheumatoid arthritis, axial spondyloarthritis, and psoriatic arthritis.
作者信息
Bilgin Emre
机构信息
Division of Rheumatology, Department of Internal Medicine, Sakarya University Faculty of Medicine, 54050, Sakarya, Turkiye.
出版信息
Ther Adv Musculoskelet Dis. 2025 Jun 21;17:1759720X251343579. doi: 10.1177/1759720X251343579. eCollection 2025.
This narrative review outlines the current applications and considerations of artificial intelligence (AI) for diagnosis, management, and prognosis in rheumatoid arthritis (RA), axial spondyloarthritis (axSpA), and psoriatic arthritis (PsA). Advances in AI, mainly in machine learning and deep learning, have significantly influenced medical research and clinical practice over the past decades by offering precisions in data understanding and treatment approaches. AI applications have enhanced risk prediction models, early diagnosis, and better management in RA. Predictive models have guided treatment decisions such as-response to methotrexate and biologics-while wearable devices and electronic health records (EHR) improve disease activity monitoring. In addition, AI applications are reported as promising for the early identification of extra-articular involvements, prediction, detection, and assessment of comorbidities. In axSpA, AI-driven models using imaging techniques such as sacroiliac radiography, magnetic resonance imaging, and computed tomography have increased diagnostic accuracy, especially for early inflammatory changes. Predictive algorithms help stratify and predict disease outcomes, while clinical decision support systems integrate clinical and imaging data for optimized management. For PsA, AI has also allowed for early detection among psoriasis patients using genetic markers, immune profiling, and EHR-based natural language processing systems. Overall, AI models may predict diagnosis, disease severity, treatment response, and comorbidities to improve care in patients with RA, axSpA, and PsA. As a rapidly developing and improving area, AI has the potential to change our current perspective of medical practice by offering better diagnostic evaluation and treatments and improved patient follow-up. Multimodal AI, focusing on collaboration, reliability, transparency, and patient-centered innovation, looks like the future of medical practice. However, data quality, model interpretability, and ethical considerations must be addressed to ensure reliable and equitable applications in clinical practice.
本叙述性综述概述了人工智能(AI)在类风湿性关节炎(RA)、轴性脊柱关节炎(axSpA)和银屑病关节炎(PsA)的诊断、管理及预后方面的当前应用和考量因素。在过去几十年中,主要在机器学习和深度学习方面的人工智能进展,通过在数据理解和治疗方法上提供精准度,显著影响了医学研究和临床实践。人工智能应用增强了RA的风险预测模型、早期诊断及更好的管理。预测模型指导了诸如对甲氨蝶呤和生物制剂的反应等治疗决策,而可穿戴设备和电子健康记录(EHR)改善了疾病活动监测。此外,据报道人工智能应用在关节外受累的早期识别、合并症的预测、检测和评估方面很有前景。在axSpA中,使用骶髂关节放射摄影、磁共振成像和计算机断层扫描等成像技术的人工智能驱动模型提高了诊断准确性,尤其是对于早期炎症变化。预测算法有助于对疾病结局进行分层和预测,而临床决策支持系统整合临床和成像数据以实现优化管理。对于PsA,人工智能还通过基因标记、免疫谱分析和基于EHR的自然语言处理系统,实现了在银屑病患者中的早期检测。总体而言,人工智能模型可以预测诊断、疾病严重程度、治疗反应和合并症,以改善RA、axSpA和PsA患者的护理。作为一个快速发展和不断改进的领域,人工智能有潜力通过提供更好的诊断评估和治疗以及改善患者随访,改变我们当前对医疗实践的看法。聚焦于协作、可靠性、透明度和以患者为中心的创新的多模态人工智能,似乎就是医疗实践的未来。然而,必须解决数据质量、模型可解释性和伦理考量等问题,以确保在临床实践中可靠且公平地应用。