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眼镜蛇毒液的肝毒性作用——一种罕见表现:病例报告

Hepatotoxic effect of elapid venom-a rare manifestation: Case report.

作者信息

Chaudhuri Partha K, Azam Nazifa, Madhur Abha, Singh Jyotsna, Kumar Ranvijay, Prasad Anupa, Sarkar Pratik

机构信息

Department of Paediatrics, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.

Department of Biochemistry, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.

出版信息

J Family Med Prim Care. 2025 May;14(5):2062-2064. doi: 10.4103/jfmpc.jfmpc_1784_24. Epub 2025 May 31.

Abstract

Snake bite is a neglected tropical disease affecting millions of people across the globe. The highest burden exists in South East Asia and Sub-Saharan Africa. Around 45900 deaths could be attributed to snake bites in India with 25% of these deaths occurring in children between age group of 5-14 years. Snake bites can broadly present with hemotoxic and neurotoxic manifestations. Management of snake envenomation comprises of first aid measures, administration of ASV (Anti-Snake Venom), strict monitoring, supportive management in the form of pain relief, correcting coagulation parameters and fluid and haemodynamic monitoring. We are reporting a case of Elapid poisoning, which besides the usual neurotoxic manifestation, also presented with hepatotoxicity which is an uncommon presentation.

摘要

蛇咬伤是一种被忽视的热带疾病,影响着全球数百万人。东南亚和撒哈拉以南非洲的负担最为沉重。在印度,约45900人死于蛇咬伤,其中25%的死亡发生在5至14岁的儿童中。蛇咬伤大致可表现为血液毒性和神经毒性表现。蛇咬伤中毒的治疗包括急救措施、抗蛇毒血清(ASV)的给药、严格监测、以止痛、纠正凝血参数以及液体和血流动力学监测等形式的支持性治疗。我们报告一例眼镜蛇科中毒病例,该病例除了常见的神经毒性表现外,还出现了肝毒性,这是一种不常见的表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/110c/12178501/a74dda5f2350/JFMPC-14-2062-g001.jpg

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