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腹腔镜根治性前列腺切除术的学习曲线

Learning curve for laparoscopic radical prostatectomy.

作者信息

Barnaś Anna, Milecki Tomasz, Ida Agnieszka, Kasperczak Michał, Lipski Adam, Antczak Andrzej, Cieślikowski Wojciech A

机构信息

Department of Urology, Poznan University of Medical Sciences, Poznań, Poland.

Department of Urology, Józef Struś Multispecialist Municipal Hospital, Poznań, Poland.

出版信息

Wideochir Inne Tech Maloinwazyjne. 2025 Feb 10;20(1):69-75. doi: 10.20452/wiitm.2025.17933. eCollection 2025 Apr 9.

Abstract

INTRODUCTION

While robotic prostatectomies are gaining popularity, laparoscopic and open surgeries remain prevalent in Central and Eastern Europe due to their cost‑effectiveness. In Poland, many urology residents report insufficient laparoscopic training. This study retrospectively evaluated the learning curve for laparoscopic radical prostatectomy (LRP).

AIM

This paper aimed to assess the learning curve of a single resident performing extraperitoneal LRP.

MATERIALS AND METHODS

We analyzed 72 patients who underwent LRP between 2016 and 2020 at a single center, divided into 5 groups (G1-G5) according to chronological order. The procedures were per‑ formed by a single urologist without on‑site supervision. Outcomes included operative duration, length of hospital stay, complications, transfusion rates, histopathology findings, biochemical recurrence, and urinary incontinence.

RESULTS

Patient characteristics were similar across all groups. The median (interquartile range [IQR]) age ranged from 61 (54-66) to 68 (66-70) years, and the median (IQR) prostate‑specific antigen con‑ centration, from 6.7 (5.4-8.5) to 15 (6.3-19.3) ng/ml. Higher Gleason scores were more common in the G3 and G4 groups (P = 0.05) than in the other groups. Surgery time decreased from 183 minutes in the G1 group to 130 minutes in the G5 group (P <0.001). The rates of positive surgical margins were the highest in the G3 and G4 groups (53.3% and 46.7%, respectively; P = 0.02). The rate of urinary continence improved from 66.7% in the G1 group to 86.7% in the G4 group (P = 0.36); however, without any significant difference among all groups. Biochemical recurrence rates tended to be lower in the G4 and G5 groups (6.7% and 8.3%, respectively), but the difference across all groups was nonsignificant. Grade III-V complications occurred only in the G1 group.

CONCLUSIONS

Surgical outcomes improved after 15 procedures, and the oncological outcomes, after 45, with functional improvement observed later. Performing hundreds of surgeries may be required to achieve high proficiency in performing LRP.

摘要

引言

虽然机器人前列腺切除术越来越受欢迎,但由于其成本效益,腹腔镜手术和开放手术在中欧和东欧仍然很普遍。在波兰,许多泌尿外科住院医师报告腹腔镜培训不足。本研究回顾性评估了腹腔镜根治性前列腺切除术(LRP)的学习曲线。

目的

本文旨在评估一名住院医师进行腹膜外LRP的学习曲线。

材料与方法

我们分析了2016年至2020年在单一中心接受LRP的72例患者,按时间顺序分为5组(G1-G5)。手术由一名泌尿外科医生在没有现场监督的情况下进行。结果包括手术时间、住院时间、并发症、输血率、组织病理学结果、生化复发和尿失禁。

结果

所有组的患者特征相似。年龄中位数(四分位间距[IQR])为61(54-66)至68(66-70)岁,前列腺特异性抗原浓度中位数(IQR)为6.7(5.4-8.5)至15(6.3-19.3)ng/ml。Gleason评分较高在G3组和G4组(P = 0.05)比其他组更常见。手术时间从G1组的183分钟降至G5组的130分钟(P <0.001)。手术切缘阳性率在G3组和G4组最高(分别为53.3%和46.7%;P = 0.02)。尿失禁率从G1组的66.7%提高到G4组的86.7%(P = 0.36);然而,所有组之间没有任何显著差异。III-V级并发症仅发生在G1组。

结论

15例手术后手术结果有所改善,45例后肿瘤学结果改善,功能改善出现较晚。可能需要进行数百例手术才能在LRP方面达到高度熟练。

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