Peng Pei-Ying, Duan Hui-Ying, Xu Lei, Sun Ji-Qin, Ma Li-Juan, Zu Ya, Yan Ting-Liang
Institute of Microbiology of Qujing Medical College, Qujing, Yunnan Province, China.
Department of Clinical Laboratory, Qujing Second People's Hospital, Qujing, Yunnan Province, China.
PLoS One. 2025 Jun 23;20(6):e0325905. doi: 10.1371/journal.pone.0325905. eCollection 2025.
Scrub typhus is a deadly infectious disease that is frequently underdiagnosed. Forecasting the emergence of infectious diseases using epidemiological models has emerged as a crucial instrument for comprehending the dynamics of their occurrence. This research aimed to investigate epidemic traits and create a predictive model for scrub typhus in mainland China, employing the Seasonal Autoregressive Integrated Moving Average (SARIMA) time series method. Monthly records of scrub typhus cases were gathered from the China Center for Disease Control and Prevention, covering the timeframe from 2006 to 2019. From 2006 to 2018, a total of 142849 scrub typhus cases were reported in China, the females' morbidity was higher than the males' one (P < 0.001). The ideal model was SARIMA (1, 0, 2) (1, 1, 1) 12 with its residual being white noise (P > 0.05). This method forecasted scrub typhus cases between January and December 2019, with the predicted values for 2019 falling within the 95% confidence range. The research indicates that the SARIMA model accurately simulated the epidemiological patterns of scrub typhus across mainland China. Utilizing the SARIMA model is a practical approach for tracking scrub typhus cases in mainland China.
恙虫病是一种常被漏诊的致命传染病。利用流行病学模型预测传染病的出现已成为理解其发生动态的关键工具。本研究旨在利用季节性自回归积分滑动平均(SARIMA)时间序列方法,调查中国大陆恙虫病的流行特征并建立预测模型。从中国疾病预防控制中心收集了2006年至2019年期间恙虫病病例的月度记录。2006年至2018年,中国共报告142849例恙虫病病例,女性发病率高于男性(P < 0.001)。理想模型为SARIMA(1, 0, 2)(1, 1, 1)12,其残差为白噪声(P > 0.05)。该方法预测了2019年1月至12月的恙虫病病例,2019年的预测值落在95%置信范围内。研究表明,SARIMA模型准确模拟了中国大陆恙虫病的流行病学模式。利用SARIMA模型是追踪中国大陆恙虫病病例的一种实用方法。