Gan Elaine Ju Yen, Yap Jun Fai, Patrick Sylves, Binson Caroline, Mary Alexander Sheena
Department of Ophthalmology, Queen Elizabeth Hospital, Sabah, Malaysia.
Institute for Public Health, National Institutes of Health, Shah Alam, Malaysia.
Ocul Immunol Inflamm. 2025 Jun 23:1-4. doi: 10.1080/09273948.2025.2519845.
Subretinal abscess is a rare but vision-threatening manifestation of endogenous endophthalmitis, accounting for approximately 5% of cases. It typically occurs in immunocompromised individuals and may be caused by a variety of microbial pathogens. We aim to highlight the importance of early recognition of subretinal abscess in a patient with preserved vision and minimal ocular symptoms.
We report a case of acute subretinal abscess secondary to Methicillin-Sensitive bacteremia in a 55-year-old man with previously undiagnosed diabetes mellitus. The patient presented with floaters in the left eye one day after undergoing incision and drainage of a lip abscess.
Visual acuity remained 6/6 in both eyes. Fundus examination of the left eye revealed a superotemporal subretinal abscess with surrounding hemorrhage and Roth spots. Blood and pus cultures confirmed methicillin-sensitive . The patient was treated with a single dose of intravitreal vancomycin and ceftazidime, along with systemic antibiotics including intravenous cloxacillin, cefazolin, and oral ciprofloxacin. Pars plana vitrectomy was deemed unnecessary due to the lesion's favorable location, size, and good presenting visual acuity. The lesion resolved with choroidoretinal scarring, and vision was preserved.
Subretinal abscess is an uncommon ocular complication of systemic infections that may be overlooked due to its subtle presentation. This case highlights the need for thorough ocular evaluation in patients with bacteremia, even in the presence of minimal visual symptoms. Early diagnosis and targeted antimicrobial therapy are crucial in preventing serious ocular morbidity and preserving vision.
视网膜下脓肿是内源性眼内炎一种罕见但威胁视力的表现形式,约占病例的5%。它通常发生在免疫功能低下的个体中,可能由多种微生物病原体引起。我们旨在强调在视力尚好且眼部症状轻微的患者中早期识别视网膜下脓肿的重要性。
我们报告一例55岁男性急性视网膜下脓肿病例,该患者继发于甲氧西林敏感菌血症,此前未诊断出患有糖尿病。患者在唇部脓肿切开引流一天后出现左眼飞蚊症。
双眼视力均保持在6/6。左眼眼底检查发现颞上视网膜下脓肿,周围有出血和 Roth 斑。血液和脓液培养证实为甲氧西林敏感菌。患者接受了单剂量玻璃体内注射万古霉素和头孢他啶治疗,同时使用包括静脉注射氯唑西林、头孢唑林和口服环丙沙星在内的全身抗生素。由于病变位置良好、大小合适且初始视力较好,因此认为无需进行玻璃体切割术。病变通过脉络膜视网膜瘢痕形成而消退,视力得以保留。
视网膜下脓肿是全身感染罕见的眼部并发症,因其表现隐匿可能被忽视。本病例强调了即使在视觉症状轻微的菌血症患者中也需要进行全面的眼部评估。早期诊断和针对性抗菌治疗对于预防严重的眼部疾病和保留视力至关重要。