Wu Tao, Ru Bao, Song Haixin, Liao Zhiping, Yang Xiaotian, Wu Fangchao, Li Jianhua
Department of Rehabilitation Medicine, National Regional Medical Center, Sir Run Run Shaw Hospital, Alaer Hospital, Zhejiang University School of Medicine, Alar City, Xinjiang, PR China.
Department of Rehabilitation Medicine, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, PR China.
Medicine (Baltimore). 2025 Jun 20;104(25):e42587. doi: 10.1097/MD.0000000000042587.
Myofascial pain syndrome (MPS) is a prevalent condition that accounts for a significant proportion of musculoskeletal pain cases. Interfascial hydrodissection (IH) represents an innovative therapeutic intervention for MPS, particularly for those patients who have not found relief through conventional treatment methods. We conducted this study to evaluate the efficacy of the ultrasound-guided IH technique with 10% dextrose solution (D10W) for treating MPS. A retrospective analysis of clinical data was conducted from MPS patients who did not respond to conventional treatments. These patients subsequently received ultrasound-guided injections of D10W. The efficacy of this treatment modality was meticulously evaluated by quantitatively measuring the reduction in pain intensity in patients across 3 distinct posttreatment conditions: at rest, at nocturnal, and during exercise. Numerical Rating Scale and EQ-5D-5L were assessed at baseline, and at 4 and 12 weeks following the final injection. The pain scores, assessed 4 and 12 weeks posttreatment, demonstrated a significant reduction compared to pretreatment levels across rest, nocturnal, and exercise states (P < .05). The EQ-5D-5L results indicated that there were no significant differences in the dimensions of mobility, self-care, and usual activities when comparing before and posttreatment (P > .05). Conversely, a significant improvement was observed in the dimensions of pain/discomfort and anxiety/depression posttreatment relative to baseline measures (P < .05). No serious adverse effects were observed. Ultrasound-guided D10W IH has demonstrated significant efficacy in improving pain and alleviating anxiety/depression in patients with refractory MPS. The outcomes are promising for individuals with MPS who have not experienced improvement with conventional medical interventions.
肌筋膜疼痛综合征（MPS）是一种常见病症，在肌肉骨骼疼痛病例中占很大比例。筋膜间液压分离术（IH）是一种针对MPS的创新治疗干预方法，尤其适用于那些通过传统治疗方法未能缓解症状的患者。我们开展这项研究，以评估超声引导下使用10%葡萄糖溶液（D10W）进行IH技术治疗MPS的疗效。对未对传统治疗产生反应的MPS患者的临床数据进行了回顾性分析。这些患者随后接受了超声引导下的D10W注射。通过定量测量患者在三种不同治疗后状态（休息时、夜间和运动时）的疼痛强度降低情况，对这种治疗方式的疗效进行了细致评估。在基线时以及最后一次注射后的第4周和第12周，对数字评定量表和EQ-5D-5L进行了评估。治疗后第4周和第12周评估的疼痛评分显示，与治疗前相比，在休息、夜间和运动状态下均有显著降低（P < 0.05）。EQ-5D-5L结果表明，在比较治疗前后的活动能力、自我护理和日常活动维度时，没有显著差异（P > 0.05）。相反，与基线测量相比，治疗后在疼痛/不适和焦虑/抑郁维度观察到显著改善（P < 0.05）。未观察到严重不良反应。超声引导下的D10W IH已证明在改善难治性MPS患者的疼痛和减轻焦虑/抑郁方面具有显著疗效。对于那些通过传统医学干预未取得改善的MPS患者来说，这些结果很有前景。
