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体位性蛋白尿患儿尿氨基酸排泄情况

Excretion of urinary amino acids in children with postural proteinuria.

作者信息

Suzuki Y, Imai I, Shimao S, Miura I K, Okada T

出版信息

Int J Pediatr Nephrol. 1985 Jul-Sep;6(3):195-8.

PMID:4055238
Abstract

The urinary excretion of free amino acids was studied in urine specimens from 12 subjects with postural proteinuria in recumbent posture and after a period of upright lordotic posture. The lordotic posture produced an increased urinary excretion of total amino acid and 12 amino acids, particularly of taurine, glutamic acid, a-amino adipic acid, valine, leucine, ethanolamine and arginine. However, 90 min after the lordotic posture, all amino acids returned to the initial values. Although, many factors must be considered in the evaluation of the urinary excretion of amino acids, an increased urinary excretion of amino acids occurring after the lordotic posture may be the result of reabsorption disturbance of the renal tubules.

摘要

对12名体位性蛋白尿患者卧位及一段时间的脊柱前凸直立姿势后的尿液样本中游离氨基酸的尿排泄情况进行了研究。脊柱前凸姿势使总氨基酸和12种氨基酸的尿排泄增加,尤其是牛磺酸、谷氨酸、α-氨基己二酸、缬氨酸、亮氨酸、乙醇胺和精氨酸。然而,脊柱前凸姿势90分钟后,所有氨基酸都恢复到初始值。虽然在评估氨基酸尿排泄时必须考虑许多因素,但脊柱前凸姿势后出现的氨基酸尿排泄增加可能是肾小管重吸收紊乱的结果。

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