超声内镜引导下乙醇消融治疗实性假乳头状肿瘤患者：四例系列报道
EUS-guided ethanol ablation in patients with solid pseudopapillary neoplasm: a four-case series.
作者信息
Myung Yousik, Hara Kazuo, Haba Shin, Kuwahara Takamichi, Okuno Nozomi, Koda Hiroki, Melianti Indria, Agyei-Nkansah Adwoa
机构信息
Department of Gastroenterology, Aichi Cancer Center, 1-1 Kanokoden, Chikusa-ku, Nagoya, 464-8681, Japan.
出版信息
Clin J Gastroenterol. 2025 Jun 24. doi: 10.1007/s12328-025-02163-6.
BACKGROUND/AIMS: Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare tumor with low malignant potential, though 10-15% may show invasive or metastatic behavior. This study aimed to evaluate the safety and efficacy of endoscopic ultrasound-guided ethanol ablation (EUS-EI) in patients with SPN who were not surgical candidates.
METHODS
Four patients with SPN who declined or were ineligible for surgery underwent EUS-EI at Aichi Cancer Center. Technical and clinical outcomes, as well as adverse events, were assessed.
RESULTS
Technical success was achieved in all patients (100%). Clinical success was observed in three patients (75%), including two with complete ablation and one with significant tumor reduction. No major adverse events or tumor recurrence occurred during follow-up.
CONCLUSIONS
EUS-EI may be a safe and effective alternative for managing SPN in non-surgical candidates.
背景/目的：胰腺实性假乳头状瘤（SPN）是一种恶性潜能较低的罕见肿瘤，不过10% - 15%的病例可能表现出侵袭性或转移行为。本研究旨在评估内镜超声引导下乙醇消融术（EUS - EI）对不适合手术的SPN患者的安全性和有效性。
方法
4例拒绝手术或不适合手术的SPN患者在爱知癌症中心接受了EUS - EI治疗。评估了技术和临床结果以及不良事件。
结果
所有患者（100%）均取得技术成功。3例患者（75%）获得临床成功，其中2例完全消融，1例肿瘤显著缩小。随访期间未发生重大不良事件或肿瘤复发。
结论
对于不适合手术的SPN患者，EUS - EI可能是一种安全有效的治疗选择。
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