Silva Yasmin F R, Martins Cleodice A, Cattafesta Monica, Haraguchi Fabiano K, Soares Fabíola L P, Pedraza Dixis F, Salaroli Luciane B
Postgraduate Program in Nutrition and Health, Health Sciences Center, Federal University of Espírito Santo, Vitória, Espírito Santo, Brazil.
Department of Nursing, State University of Paraíba, João Pessoa, Paraíba, Brazil.
Nutrition. 2025 Nov;139:112853. doi: 10.1016/j.nut.2025.112853. Epub 2025 May 22.
Central obesity is a significant risk factor for cardiovascular disease. The Conicity Index (C-Index), an anthropometric indicator based on the idea that fat accumulation around the waist favors a change in body shape from a cylinder to a double cone, is a predictor of several diseases, including cardiovascular events. This study aimed to establish cut-off points for the C-Index in the Brazilian adult population based on the Framingham cardiovascular risk score.
This cross-sectional study used secondary data from the 2013 National Health Survey. The sample consisted of 6111 individuals. ROC curve analysis was conducted to determine the cut-off point of the C-Index according to cardiovascular risk calculated from the Framingham score. Cut-off points were defined according to specificity, sensitivity, and the Youden index. The C-Index cut-off point for predicting cardiovascular risk was found to be 1.285 for women and 1.344 for men.
The results of this study indicate that individuals with a C-Index above these established values are at high risk of developing an initial cardiovascular event within the next 10 years. These findings are applicable to the entire Brazilian adult population aged 30-74 years and can be used to guide chronic disease prevention actions at the individual and population levels, to assess the nutritional status of population groups, and to develop public policy strategies related to non-communicable diseases.
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