一只幼犬的局灶性肉芽肿性脑膜脑脊髓炎。
Focal granulomatous meningoencephalomyelitis in a pup.
作者信息
Murtaugh R J, Fenner W R, Johnson G C
出版信息
J Am Vet Med Assoc. 1985 Oct 15;187(8):835-6.
Granulomatous meningoencephalomyelitis (GME) was diagnosed in an 8-month-old Maltese with signs of CNS disease. Serum immunoglobulin (Ig) G concentration was decreased, and CSF analysis revealed high concentrations of mononuclear WBC and IgG. Initial improvement of the pup's signs in association with prednisolone treatment and postmortem examination of CNS tissues confirmed GME. Granulomatous meningoencephalomyelitis occurs rarely in young dogs and the abnormal Ig concentrations in this pup's serum and CSF suggest that immune responses may have a role in the cause and/or pathogenesis of GME.
一只8个月大出现中枢神经系统疾病症状的马尔济斯犬被诊断为肉芽肿性脑膜脑脊髓炎（GME）。血清免疫球蛋白（Ig）G浓度降低，脑脊液分析显示单核白细胞和IgG浓度升高。幼犬的症状在泼尼松龙治疗后初步改善，中枢神经系统组织的尸检证实了GME。肉芽肿性脑膜脑脊髓炎在幼犬中很少见，这只幼犬血清和脑脊液中异常的Ig浓度表明免疫反应可能在GME的病因和/或发病机制中起作用。
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