与后路腰椎椎间融合术相比,前路腰椎椎间融合术是否能降低成人脊柱畸形手术中腰骶部的机械并发症和假关节形成率?

Does Anterior Lumbar Interbody Fusion Reduce Mechanical Complication and Pseudarthrosis Rate at the Lumbosacral Junction in Adult Spinal Deformity Surgery in Comparison to Posterior Lumbar Interbody Fusion?

作者信息

Mohamed Mohamed Kamal A, Rauschmann Michael, Slavici Andrei, Rickert Marcus, Walter Sebastian, Kernich Nikolaus, Sircar Krishnan, Eysel Peer, Heck Vincent J

机构信息

Goethe University School of Medicine and University Hospital Frankfurt am Main, Department of Orthopaedic Surgery, Goethe University Frankfurt, Frankfurt am Main, Germany

Centre for Complex Spine Service and Reconstructive Orthopaedic Surgery, Sana Academic Teaching Hospital, Offenbach am Main, Germany.

出版信息

Int J Spine Surg. 2025 Sep 2;19(4):409-417. doi: 10.14444/8774.

Abstract

BACKGROUND

To evaluate the impact of anterior lumbar interbody fusion (ALIF) vs posterior lumbar interbody fusion (PLIF) at the lumbosacral junction on mechanical complications and fusion rate at the caudal lumbar segments in adult spinal deformity (ASD) surgery.

METHODS

This retrospective cohort study included ASD patients with coronal or sagittal imbalance who underwent thoracolumbar to pelvic fusion with ALIF or PLIF technique at the lumbosacral junction and a minimum follow-up of 2 years. The primary focus was on mechanical complications, including material failure and sacral fracture, implant-related pain, pseudarthrosis, and reoperation. Patient-specific and perioperative characteristics were also analyzed at the 2-year follow-up. The primary focus was on mechanical complications, including material failure and sacral fracture, implant-related pain, pseudarthrosis, and reoperation. Patient-specific and perioperative characteristics were also analyzed.

RESULTS

A total of 56 patients were included, comprising 32 ALIF and 24 PLIF patients, with a mean age of 79.5 ± 6.6 years. The overall mechanical complication rate was 19.6%, including screw loosening (7.1%), rod breakage (5.4%), sacral fracture (3.6%), and screw breakage (1.8%). Pseudarthrosis and reoperation rates were 10.7% each. ALIF significantly reduced mechanical complications compared with PLIF (9.4% vs 37.5%, = 0.011). The ALIF group also showed lower rates of pseudarthrosis, implant-related pain, and reoperation ( < 0.05). Regression analysis identified PLIF as an independent risk factor for mechanical complications ( = 0.006). Length of hospital stay, operative time, and pseudarthrosis rate were significantly associated with an increased rate of mechanical complications, but patient demographics had no significant impact.

CONCLUSION

Approximately 1 in 5 patients experiences mechanical complications within 2 years of ASD correction surgery. ALIF at the lumbosacral junction significantly reduces mechanical complications and pseudarthrosis compared with PLIF, resulting in lower reoperation rates. These findings suggest that ALIF should be the preferred technique for lumbosacral fusion in long-segment ASD constructs, provided there is no spondylolisthesis or severe spinal stenosis with L5 nerve root compression requiring simultaneous direct posterior decompression and fusion. This is particularly important in patients at risk for mechanical complications and pseudarthrosis, including those undergoing revision procedures.

LEVEL OF EVIDENCE

3 - Retrospective comparative study.

摘要

背景

评估在成人脊柱畸形(ASD)手术中,腰骶部前路腰椎椎间融合术(ALIF)与后路腰椎椎间融合术(PLIF)对下腰椎节段机械性并发症及融合率的影响。

方法

这项回顾性队列研究纳入了患有冠状面或矢状面失衡的ASD患者,这些患者在腰骶部接受了胸腰段至骨盆的ALIF或PLIF技术融合术,且至少随访2年。主要关注机械性并发症,包括材料失效和骶骨骨折、植入物相关疼痛、假关节形成及再次手术。在2年随访时还分析了患者个体特征和围手术期特征。主要关注机械性并发症,包括材料失效和骶骨骨折、植入物相关疼痛、假关节形成及再次手术。同时也分析了患者个体特征和围手术期特征。

结果

共纳入56例患者,其中32例行ALIF,24例行PLIF,平均年龄79.5±6.6岁。总体机械性并发症发生率为19.6%,包括螺钉松动(7.1%)、棒材断裂(5.4%)、骶骨骨折(3.6%)和螺钉断裂(1.8%)。假关节形成率和再次手术率均为10.7%。与PLIF相比,ALIF显著降低了机械性并发症发生率(9.4%对37.5%,P = 0.011)。ALIF组的假关节形成率、植入物相关疼痛率和再次手术率也较低(P < 0.05)。回归分析确定PLIF是机械性并发症的独立危险因素(P = 0.006)。住院时间、手术时间和假关节形成率与机械性并发症发生率增加显著相关,但患者人口统计学特征无显著影响。

结论

在ASD矫正手术2年内,约五分之一的患者会发生机械性并发症。与PLIF相比,腰骶部的ALIF显著降低了机械性并发症和假关节形成率,从而降低了再次手术率。这些结果表明,在长节段ASD结构的腰骶部融合中,若不存在椎体滑脱或伴有L5神经根受压的严重椎管狭窄需要同时进行直接后路减压和融合,ALIF应是首选技术。这对于有机械性并发症和假关节形成风险的患者,包括接受翻修手术的患者尤为重要。

证据水平

3 - 回顾性比较研究。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索