Kim Minjung, Choi Seongmin, Yun Dong Hwan, Soh Yunsoo, Won Chang Won
Department of Rehabilitation Medicine, Seoul National University Hospital, Seoul 03080, Republic of Korea.
Department of Rehabilitation Medicine, Seoul National University Bundang Hospital, Seongnam 13620, Republic of Korea.
Medicina (Kaunas). 2025 Jun 10;61(6):1065. doi: 10.3390/medicina61061065.
: Sarcopenia is a major risk factor for falls in older adults. The 2023 Korean Working Group on Sarcopenia (KWGS) introduced revised definitions, including functional sarcopenia, which considers low strength and performance despite normal muscle mass. This study investigated the prevalence of sarcopenia, severe sarcopenia, and functional sarcopenia using the KWGS criteria and their association with fall risk by sex and fall frequency. : A cross-sectional analysis was conducted using data from 2061 community-dwelling Korean adults aged 70-84 years who participated in the Korean Frailty and Aging cohort study. Sarcopenia was classified based on muscle mass, grip strength, and four physical performance tests. Fall experiences in the past year were categorized as ≥1, ≥2, and ≥4 falls. Logistic regression analyses were performed separately according to sex to evaluate the association between sarcopenia definition and fall risk. : The prevalence of sarcopenia and severe sarcopenia was 32.9% and 10.1% in men and 21.5% and 5.0% in women, respectively. Functional sarcopenia was more prevalent in women (10.5%) than in men (5.1%). In men, sarcopenia (defined using gait speed) was associated with fall risk across all thresholds (odds ratio [OR] = 2.28 for ≥1 fall; OR = 5.64 for ≥4 falls). In women, sarcopenia (defined using gait speed) was associated with ≥1 fall (OR = 1.72), while functional sarcopenia (defined using gait speed and timed up-and-go test) was associated with frequent falls (OR = 3.79-3.87). : The 2023 KWGS guidelines revealed sex-specific differences in the prevalence of sarcopenia and highlighted gait speed as a key predictor of fall risk in men, whereas functional sarcopenia was more prevalent in women. Limitations include the cross-sectional design and use of self-reported fall data, which may be subject to recall bias.
肌肉减少症是老年人跌倒的主要风险因素。2023年韩国肌肉减少症工作组(KWGS)引入了修订后的定义,包括功能性肌肉减少症,该定义考虑了尽管肌肉质量正常但力量和功能低下的情况。本研究使用KWGS标准调查了肌肉减少症、严重肌肉减少症和功能性肌肉减少症的患病率,以及它们与按性别和跌倒频率划分的跌倒风险之间的关联。:使用来自2061名年龄在70 - 84岁的韩国社区居住成年人的数据进行了横断面分析,这些人参与了韩国衰弱与衰老队列研究。肌肉减少症根据肌肉质量、握力和四项身体功能测试进行分类。过去一年的跌倒经历分为≥1次、≥2次和≥4次跌倒。根据性别分别进行逻辑回归分析,以评估肌肉减少症定义与跌倒风险之间的关联。:男性肌肉减少症和严重肌肉减少症的患病率分别为32.9%和10.1%,女性分别为21.5%和5.0%。功能性肌肉减少症在女性中(10.5%)比在男性中(5.1%)更普遍。在男性中,肌肉减少症(使用步速定义)在所有阈值下都与跌倒风险相关(≥1次跌倒的比值比[OR]=2.28;≥4次跌倒的OR = 5.64)。在女性中,肌肉减少症(使用步速定义)与≥1次跌倒相关(OR = 1.72),而功能性肌肉减少症(使用步速和计时起立行走测试定义)与频繁跌倒相关(OR = 3.79 - 3.87)。:2023年KWGS指南揭示了肌肉减少症患病率的性别差异,并强调步速是男性跌倒风险的关键预测因素,而功能性肌肉减少症在女性中更普遍。局限性包括横断面设计和使用自我报告的跌倒数据,这可能存在回忆偏差。