血友病患者进行冠状动脉搭桥手术是否安全？4例患者的病例系列报道
Is it safe to perform coronary artery bypass grafting surgery in patients with hemophilia? A case series of four patients.
作者信息
Köseoğlu Fatoş Dilan, Demirci Zühal, Kahraman Ümit, Saydam Güray, Şahin Fahri
机构信息
Department of Internal Medicine, Division of Hematology, Bakırçay University Faculty of Medicine, İzmir, Türkiye.
Ege University Hospital, Thrombosis and Hemostasis Center, İzmir, Türkiye.
出版信息
Turk Gogus Kalp Damar Cerrahisi Derg. 2025 Apr 30;33(2):251-256. doi: 10.5606/tgkdc.dergisi.2025.25800. eCollection 2025 Apr.
Hemophilia is a genetic disorder that mainly affects males and leads to a higher risk of bleeding. There is a lack of clarity regarding the safety of coronary artery bypass grafting (CABG) surgery in patients with hemophilia. In this case series, real-life data of four male hemophilia patients aged 45 to 66 years who underwent CABG was presented. One patient needed to undergo reexploration due to nonsurgical bleeding. However, all patients were discharged in good condition. The current experience revealed that CABG in hemophilia patients is safe to perform with a multidisciplinary approach involving hematologists, anesthesiologists, and cardiovascular surgeons.
血友病是一种主要影响男性的遗传性疾病，会导致出血风险增加。血友病患者进行冠状动脉旁路移植术（CABG）手术的安全性尚不清楚。在本病例系列中，展示了4名年龄在45至66岁之间接受CABG手术的男性血友病患者的真实数据。1名患者因非手术性出血需要再次手术探查。然而，所有患者均康复出院。目前的经验表明，血友病患者进行CABG手术在血液科医生、麻醉科医生和心血管外科医生参与的多学科方法下是安全可行的。
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