Ohhara M, Okumura S, Tsuboi N, Kanamori S, Yoshida K, Nishimura T, Akimoto M, Ohki I
Hinyokika Kiyo. 1985 Jun;31(6):1045-8.
A case of massive cyclophosphamide hemorrhagic cystitis is presented. A 47-year-old woman with Evans syndrome was treated with a total dose of 56.6 g of cyclophosphamide for 2 years. Six months after the cessation of administration, massive hemorrhagic cystitis suddenly occurred following a common cold. Embolization of bilateral internal iliac arteries was ineffective. Therefore we performed transurethral electrocoagulation broadly for bleeding mucosa. The day after operation, bleeding from the bladder remarkably decreased and further transfusions were hardly required.
本文报告一例大剂量环磷酰胺所致出血性膀胱炎病例。一名47岁患有伊文氏综合征的女性接受了为期2年、总量达56.6g的环磷酰胺治疗。停药6个月后，因普通感冒突然发生大量出血性膀胱炎。双侧髂内动脉栓塞无效。因此，我们对出血黏膜进行了广泛的经尿道电凝术。术后第二天，膀胱出血明显减少，几乎不再需要进一步输血。
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