Compagnoni Riccardo, Klasan Antonio, Grassi Alberto, Puglia Francesco, Zaffagnini Stefano, Randelli Pietro Simone, Menetrey Jacques
Clinica Ortopedica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO Milan Italy.
Department of Biomedical, Surgical and Dental Sciences Università degli Studi di Milano Milan Italy.
J Exp Orthop. 2025 Jul 2;12(3):e70312. doi: 10.1002/jeo2.70312. eCollection 2025 Jul.
This systematic review aims to investigate the knee flexion angles used for graft fixation in lateral extra-articular tenodesis (LET) during anterior cruciate ligament reconstruction (ACLR) and their impact on clinical outcomes.
Following PRISMA guidelines, MEDLINE/PubMed and EMBASE were searched up to February 2024. The inclusion criteria were original clinical studies (levels I-IV evidence) with at least 12 months of follow-up, reporting knee flexion angles during LET graft fixation in ACLR. Exclusion criteria included non-English articles, reviews, biomechanical studies, and case reports. Data on study design, patient numbers, fixation angles, and clinical outcomes were extracted, and study quality was assessed using the RoB 2 tool.
Out of 1134 studies identified, 21 met the inclusion criteria. The reported flexion angles for LET graft fixation ranged from full extension to 90°. Ten studies fixed the graft at 30°, consistently showing improved knee stability, reduced pivot-shift rates, and better functional outcomes, especially in high-risk patients. Three studies focused on graft fixation at 45° of flexion. Another four studies investigated fixation at 60° of knee flexion. Lastly, two studies assessed outcomes with fixation at 90°.
LET combined with ACLR effectively restores knee stability across various flexion angles. While fixation at 30° is most commonly associated with positive outcomes, the lack of consensus on an optimal angle reflects differences in surgical techniques and patient-specific factors. Further prospective research with long-term follow-up is needed to validate these findings and guide clinical practice toward optimal knee flexion angles for graft fixation in LET procedures.
Level III.
本系统评价旨在研究前交叉韧带重建(ACLR)术中外侧关节外肌腱固定术(LET)中用于移植物固定的屈膝角度及其对临床结局的影响。
按照PRISMA指南,检索截至2024年2月的MEDLINE/PubMed和EMBASE数据库。纳入标准为至少随访12个月的原始临床研究(I-IV级证据),报告ACLR术中LET移植物固定时的屈膝角度。排除标准包括非英文文章、综述、生物力学研究和病例报告。提取关于研究设计、患者数量、固定角度和临床结局的数据,并使用RoB 2工具评估研究质量。
在1134项检索到的研究中,21项符合纳入标准。报道的LET移植物固定屈膝角度范围从完全伸直至90°。10项研究将移植物固定在30°,始终显示膝关节稳定性改善、轴移率降低和功能结局更好,尤其是在高危患者中。3项研究聚焦于屈膝45°时的移植物固定。另外4项研究调查了屈膝60°时的固定情况。最后,2项研究评估了屈膝90°固定时的结局。
LET联合ACLR可在不同屈膝角度有效恢复膝关节稳定性。虽然30°固定最常与良好结局相关,但对于最佳角度缺乏共识反映了手术技术和患者个体因素的差异。需要进一步进行长期随访的前瞻性研究来验证这些发现,并指导临床实践确定LET手术中移植物固定的最佳屈膝角度。
III级。