Suppr超能文献

迈向无阿片类药物的全髋关节置换术:一项针对229例患者的阿片类药物减量计划的回顾性研究。

Toward Opioid-Free Total Hip Arthroplasty: A Retrospective Study of a Targeted Opioid Reduction Program in 229 Patients.

作者信息

Noyes Mary L, Faour Kamli N W, Walsh Zoë A, Call Catherine M, Mackenzie Johanna A, Rana Adam J

机构信息

Tufts University School of Medicine, Boston, MA, USA.

MMP Orthopedics & Sports Medicine, Maine Medical Center, Portland, ME, USA.

出版信息

Arthroplast Today. 2025 Jun 20;34:101726. doi: 10.1016/j.artd.2025.101726. eCollection 2025 Aug.

Abstract

BACKGROUND

Prescription opioids leftover following arthroplasty surgery pose risks to patients and communitys. The purpose of this study was to capture opioid utilization patterns following primary total hip arthroplasty before and after a targeted intervention to decrease postoperative opioid prescription quantity. We hypothesized that reducing discharge pill count would not impact pain or functional outcomes.

METHODS

Primary total hip arthroplasties performed by a high-volume, fellowship-trained arthroplasty surgeon between October 2022 and January 2024 were retrospectively evaluated for study inclusion; 229 patients met inclusion criteria. Beginning in April 2023, the surgeon gradually implemented a 38% reduction in postoperative opioid prescribing from 40 to 24 pills. Opioid consumption was evaluated by patient-reported pill count at the first postoperative visit. Patients were sorted into 2 groups: "preintervention" (n = 157) and "postintervention" (poI) (n = 72). Preintervention patients received between 300 and 420 oral morphine equivalents and poI patients received between 240 and 299.99 oral morphine equivalents. Demographics, pill counts, refills, 30-day emergency department visits, function (Hip Disability and Osteoarthritis Outcome Score Joint Replacement), pain (visual analog scale), and satisfaction scores were analyzed.

RESULTS

Proportion of discharge prescription remaining at 2-week postoperative visit did not differ significantly between intervention groups ( = .33). There were no differences in opioid refill requests ( = .82), function ( = .75), or satisfaction with functional improvement ( = .61). Patients in the poI group reported lower pain at 6 weeks postoperatively ( < .05). There were no differences in 30-day emergency department visits between groups ( = .57).

CONCLUSIONS

Results support that arthroplasty surgeons can prescribe smaller quantities of opioids without compromising care. Such interventions can help reduce the number of prescription opioids available for misuse and diversion.

摘要

背景

关节置换术后剩余的处方阿片类药物对患者和社区构成风险。本研究的目的是在采取有针对性的干预措施以减少术后阿片类药物处方量之前和之后,了解初次全髋关节置换术后阿片类药物的使用模式。我们假设减少出院时的药片数量不会影响疼痛或功能结果。

方法

回顾性评估2022年10月至2024年1月期间由一位经验丰富、接受过专科培训的关节置换外科医生进行的初次全髋关节置换术,以纳入研究;229例患者符合纳入标准。从2023年4月开始,该外科医生逐渐将术后阿片类药物处方量从40片减少38%至24片。通过患者报告的术后首次就诊时的药片数量来评估阿片类药物的消耗量。患者被分为两组:“干预前”(n = 157)和“干预后”(poI)(n = 72)。干预前患者接受300至420口服吗啡当量,干预后患者接受240至299.99口服吗啡当量。分析了人口统计学、药片数量、续方情况、30天内急诊就诊次数、功能(髋关节残疾和骨关节炎结果评分关节置换)、疼痛(视觉模拟量表)和满意度评分。

结果

干预组之间术后2周复诊时出院处方剩余比例无显著差异( = 0.33)。阿片类药物续方请求( = 0.82)、功能( = 0.75)或对功能改善的满意度( = 0.61)方面没有差异。干预后组患者术后6周报告疼痛较轻( < 0.05)。两组之间30天内急诊就诊次数没有差异( = 0.57)。

结论

结果支持关节置换外科医生可以开具较少量的阿片类药物而不影响治疗效果。此类干预措施有助于减少可供滥用和转移的处方阿片类药物数量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c4d/12221641/ae49dd4780ed/gr1.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验