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颅额鼻发育不良:一例报告。

Craniofrontonasal dysplasia: A case report.

作者信息

Ghosh Kanad, Xu Hope, Roy Mélissa, Yamini Bakhtiar, Reid Russell R

机构信息

Section of Plastic and Reconstructive Surgery Department of Surgery University of Chicago Chicago Illinois USA.

Department of Neurosurgery University of Chicago Chicago Illinois USA.

出版信息

Pediatr Discov. 2023 Jun 10;1(1):e5. doi: 10.1002/pdi3.5. eCollection 2023 Jun.

Abstract

Craniofrontonasal dysplasia (CFND) is a rare congenital malformation, which has a wide array of symptoms that can vary drastically between patients. These include coronal synostosis with associated brachycephaly, hypertelorism, cleft lip and palate, and limb malformations, among others. The pleomorphic nature of the disease and numerous clinical decisions required for its management present a unique challenge to craniofacial surgeons when considering indications and timing for surgical intervention. In this report, we present the case of a patient with CFND, their surgical management, and discuss updates in principles of management of CFND.

摘要

颅额鼻发育不良(CFND)是一种罕见的先天性畸形,其症状多种多样,患者之间差异很大。这些症状包括冠状缝早闭伴短头畸形、眼距过宽、唇腭裂以及肢体畸形等。该疾病的多形性本质以及治疗所需的众多临床决策,在考虑手术干预的适应症和时机时,给颅面外科医生带来了独特的挑战。在本报告中,我们介绍了一名CFND患者的病例、其手术治疗情况,并讨论了CFND治疗原则的最新进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db6a/12118166/1660741a8535/PDI3-1-e5-g002.jpg

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