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沙特阿拉伯王国在海湾合作委员会、东地中海区域和中东及北非地区的结核病发病率趋势,以实现世界卫生组织和联合国的可持续发展目标终结结核病战略目标。

TB Incidence Trends in the Kingdom of Saudi Arabia within the GCC, EMR, and MENA Regions, to Achieve the WHO and UN's SDG End TB Strategy Targets.

作者信息

Barry Mazin

机构信息

Infectious Disease Unit, Department of Internal Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Division of Infectious Diseases, Faculty of Medicine, University of Ottawa, Ottawa, Canada.

出版信息

J Epidemiol Glob Health. 2025 Jul 8;15(1):96. doi: 10.1007/s44197-025-00442-6.

Abstract

OBJECTIVES

To assess the tuberculosis (TB) incidence trends, between 2000 and 2023, in the Kingdom of Saudi Arabia (KSA), in comparison to that in different geopolitical regions where the KSA is commonly included within, and to determine whether the KSA achieved the World Health Organization (WHO) and the United Nations (UN) Sustainable Development Goals (SDGs) End TB Strategy milestones and targets, including the reduction of the total TB incidence by 20% in 2020 compared to that of 2015.

METHODS

This is a retrospective observational study on the TB incidence per 100,000 population arising in a given year as reported annually to the WHO. The data was extracted from the WHO indicator dataset. TB incidence data from the KSA, the World, the Gulf Cooperation Council (GCC), the Eastern Mediterranean region (EMR), and the Middle East and North Africa (MENA) region were included. Descriptive analysis and chi-square test were used to compare incidence differences and their statistical significance.

RESULTS

The TB incidence per 100,000 population in KSA in 2023 was 8.4 (95% uncertainty interval [UI]: 7.6–9.3), in 2020 it was 8.7 (95% UI:7.7–9.6), in 2015 it was 12 (95% UI: 11–13), in 2000 it was 23 (95% UI: 21–26). Compared to 2023, the reduction from 2000, 2015, and 2020 were − 14.6 (63.5%  < 0.01), − 3.6 (30%), and − 0.3 (3.4%), respectively. Compared to 2015, the reduction in 2020 was − 3.3 (27.5%). For 2023, compared to the GCC countries, the KSA had the second lowest incidence after the United Arab Emirates (UAE), which was − 7.6 less than KSA ( < 0.01). The incidence in Qatar was the highest, which was + 26.6 higher than KSA ( < 0.01). Compared to the MENA and EMR, only Jordan had a lower incidence, which was − 5.0 less than KSA. Pakistan had the highest incidence rate and the highest difference from the KSA by + 268.6 ( < 0.01).

CONCLUSION

TB incidence trends are decreasing in KSA, and it is among the top three regional countries with the lowest incidence rates. Compared with 2015, KSA exceeded the 20% milestone by achieving a 27.5% reduction in 2020. The KSA is heading towards achieving the WHO and UN’s SDG End TB Strategy targets of a 50% reduction by 2025, 80% by 2030, and 90% by 2035, to fulfill the vision of a world free of TB.

摘要

目的

评估2000年至2023年沙特阿拉伯王国(KSA)的结核病(TB)发病率趋势,并与通常将沙特阿拉伯王国纳入其中的不同地缘政治区域的发病率趋势进行比较,同时确定沙特阿拉伯王国是否实现了世界卫生组织(WHO)和联合国(UN)可持续发展目标(SDGs)终结结核病战略的里程碑和目标,包括到2020年将结核病总发病率相比2015年降低20%。

方法

这是一项回顾性观察研究,研究对象为每年向WHO报告的特定年份中每10万人口的结核病发病率。数据从WHO指标数据集中提取。纳入了沙特阿拉伯王国、全球、海湾合作委员会(GCC)、东地中海区域(EMR)以及中东和北非(MENA)区域的结核病发病率数据。采用描述性分析和卡方检验来比较发病率差异及其统计学意义。

结果

2023年沙特阿拉伯王国每10万人口的结核病发病率为8.4(95%不确定区间[UI]:7.6 - 9.3),2020年为8.7(95% UI:7.7 - 9.6),2015年为12(95% UI:11 - 13),2000年为23(95% UI:21 - 26)。与2023年相比,2000年、2015年和2020年的降幅分别为−14.6(63.5%  < 0.01)、−3.6(30%)和−0.3(3.4%)。与2015年相比,2020年的降幅为−3.3(27.5%)。2023年,与GCC国家相比,沙特阿拉伯王国的发病率在阿联酋(UAE)之后排第二低,比沙特阿拉伯王国低−7.6(<0.01)。卡塔尔的发病率最高,比沙特阿拉伯王国高+26.6(<0.01)。与MENA和EMR相比,只有约旦的发病率较低,比沙特阿拉伯王国低−5.0。巴基斯坦的发病率最高,与沙特阿拉伯王国的差异最大,为+268.6(<0.01)。

结论

沙特阿拉伯王国的结核病发病率趋势在下降,并跻身发病率最低的三个地区国家之列。与中国相比,沙特阿拉伯王国在2020年实现了27.5%的降幅,超过了20%的里程碑。沙特阿拉伯王国正朝着实现WHO和UN的SDG终结结核病战略目标迈进,即到2025年降低50%,到2030年降低80%,到2035年降低90%,以实现无结核病世界的愿景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5fd/12237834/45f8cdce2bef/44197_2025_442_Fig1_HTML.jpg

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