经卵圆孔未闭处移动的血栓导致脾梗死
Thrombus in Transit Through Patent Foramen Ovale Causing Splenic Infarction.
作者信息
Rashwan Rana, Rizk Judy, Etman Ingy, Zokailah Anhar, Kholeif Zeyad
机构信息
Cardiovascular Department, Mayo Clinic, Rochester, Minnesota, USA; Alexandria Main University Hospital, Alexandria, Egypt.
Alexandria Main University Hospital, Alexandria, Egypt.
出版信息
JACC Case Rep. 2025 Jul 9;30(18):103924. doi: 10.1016/j.jaccas.2025.103924.
BACKGROUND
Patent foramen ovale (PFO) is often asymptomatic but can cause paradoxical embolism. Although cryptogenic stroke is common, this case is unique due to splenic infarction and a visible thrombus in transit.
CASE SUMMARY
A 30-year-old woman presented with acute dyspnea, hemoptysis, and left upper quadrant abdominal pain. Investigations revealed deep vein thrombosis complicated by pulmonary embolism and paradoxical embolization through PFO, leading to splenic infarction-a rare sequence of events.
CONCLUSIONS
Screening for PFO should be considered in patients with venous thrombosis and cryptogenic embolism. Thrombus in transit through PFO presents a challenge due to the lack of consensus on management.
背景
卵圆孔未闭（PFO）通常无症状，但可导致反常栓塞。尽管隐源性卒中很常见，但该病例因脾梗死和可见的移行血栓而独特。
病例摘要
一名30岁女性出现急性呼吸困难、咯血和左上腹疼痛。检查发现深静脉血栓形成并发肺栓塞，以及通过PFO的反常栓塞，导致脾梗死——这是一系列罕见的事件。
结论
对于静脉血栓形成和隐源性栓塞患者，应考虑筛查PFO。由于在管理方面缺乏共识，通过PFO的移行血栓带来了挑战。
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