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人工关节周围感染中间隔器脱位后的伸肌机制损伤/功能障碍:单一参考中心的病例系列

Extensor mechanism injury/failure following spacer dislocation in periprosthetic joint infection: a case series in a single reference center.

作者信息

Mei A, Scazzarriello M, Brioschi D, Larghi M, Manzotti A

机构信息

University of Milan, Milan, Italy.

Luigi Sacco Hospital, Milan, Italy.

出版信息

Musculoskelet Surg. 2025 Jul 12. doi: 10.1007/s12306-025-00907-8.

Abstract

Antibiotic-loaded spacers are widely used in the two-stage revision protocol for managing periprosthetic joint infections (PJIs) of the knee, offering effective local antibiotic delivery while maintaining joint space and soft tissue tension. However, despite their clinical benefits, complications such as extensor mechanism rupture remain under-recognized and can severely compromise functional outcomes. This retrospective case series presents consecutive patients treated between 2014 and 2022 by a single orthopedic team at our institution. All patients were diagnosed with knee PJI and experienced extensor mechanism rupture following the implantation of either static or dynamic antibiotic-loaded spacers. The analysis highlights the multifactorial etiology of this complication, including factors such as severe bone loss, suboptimal spacer positioning or design, repeated debridements, and individual patient risks such as obesity and previous surgical history. Dynamic spacers, while allowing partial joint mobility, were associated with a higher risk of mechanical overload, whereas static spacers posed risks related to rigidity and stress transmission. Surgical management in all cases involved radical debridement, assessment of bone loss and femoral canal diameter, and careful selection of spacer type. Awareness of the potential for extensor mechanism injury should inform both surgical technique and postoperative care strategies.

摘要

载抗生素间隔物广泛应用于膝关节假体周围感染(PJI)的两阶段翻修方案中,可在维持关节间隙和软组织张力的同时实现有效的局部抗生素递送。然而,尽管它们具有临床益处,但诸如伸肌机制断裂等并发症仍未得到充分认识,并且会严重影响功能结局。本回顾性病例系列介绍了2014年至2022年间由我们机构的一个骨科团队连续治疗的患者。所有患者均被诊断为膝关节PJI,并在植入静态或动态载抗生素间隔物后发生伸肌机制断裂。分析突出了该并发症的多因素病因,包括严重骨丢失、间隔物定位或设计欠佳、反复清创以及肥胖和既往手术史等个体患者风险等因素。动态间隔物虽然允许部分关节活动,但与机械过载的较高风险相关,而静态间隔物则存在与刚性和应力传递相关的风险。所有病例的手术管理都包括彻底清创、评估骨丢失和股骨髓腔直径,以及仔细选择间隔物类型。对伸肌机制损伤可能性的认识应指导手术技术和术后护理策略。

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