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老年患者的腹腔镜胆囊切除术:避免还是加快?——一项比较队列研究。

Laparoscopic cholecystectomy in elderly patients: Avoid or expedite? - A comparative cohort study.

作者信息

Mondragon Maria, Mohamedahmed Ali Yasen, Zaman Shafquat, Farquharson Ja'quay, Raja Usman, Ijaz Arhum, Singh-Ranger Deepak

机构信息

Department of General Surgery, The Royal Wolverhampton NHS Trust, Wolverhampton, UK.

Department of General Surgery, The Dudley Group NHS Trust, Dudley, UK.

出版信息

J Minim Access Surg. 2025 Jul 1;21(3):265-269. doi: 10.4103/jmas.jmas_138_24. Epub 2025 Jul 14.

Abstract

INTRODUCTION

Although laparoscopic cholecystectomy (LC) has become the gold standard for treating gall bladder stones (GBS), its safety in elderly patients is still questioned. This study aimed to assess the outcome of LC in patients 70 and older compared to younger patients.

PATIENTS AND METHODS

The medical records of 548 patients undergoing LC were evaluated retrospectively. Patients' demographics and post-operative complications were recorded. Furthermore, patients were divided according to the CEPOD into emergency and elective patients, and complications were recorded according to Clavien-Dindo (CD) classifications. Data analysis was performed with SPSS software version 27.

RESULTS

Patients were divided into the elderly patients group (≥70 years of age, n = 185) and the young patients group (<70 years of age, n = 363). The ≥70-year-old group showed a significantly higher number of patients who required emergency admission with GBS symptoms (P = 0.001), emergency LC (P = 0.01) and conversion to open (P = 0.02). The two groups showed comparable post-operative complications: bile leak (P = 0.26), collection (P = 0.11) and re-operation (P = 0.60), post-operative endoscopic retrograde cholangiopancreatography (P = 1.0), GBS pancreatitis (P = 0.33) and death (0.30). CD I-II complications were higher in the ≥ 70-year-old group compared to the <70-year-old group in elective (P = 0.01) and emergency (P = 0.03) LC. However, CD ≥3 complications were higher in the ≥70-year-old group than the <70-year-old group in the emergency LC (P = 0.01) and comparable in the elective LC (P = 0.12).

CONCLUSION

LC is safe and efficient in elderly patients. Elective LC should be expedited in elderly patients to avoid emergency admissions and emergency LC, which are associated with higher complication rates.

摘要

引言

尽管腹腔镜胆囊切除术(LC)已成为治疗胆囊结石(GBS)的金标准,但其在老年患者中的安全性仍受到质疑。本研究旨在评估70岁及以上患者与年轻患者相比接受LC的结果。

患者与方法

回顾性评估548例行LC患者的病历。记录患者的人口统计学资料和术后并发症。此外,根据CE POD将患者分为急诊和择期患者,并根据Clavien-Dindo(CD)分类记录并发症。使用SPSS 27版软件进行数据分析。

结果

患者分为老年患者组(≥70岁,n = 185)和年轻患者组(<70岁,n = 363)。≥70岁组中因GBS症状需要急诊入院的患者数量(P = 0.001)、急诊LC(P = 0.01)和转为开腹手术(P = 0.02)显著更高。两组术后并发症相当:胆漏(P = 0.26)、积液(P = 0.11)和再次手术(P = 0.60)、术后内镜逆行胰胆管造影(P = 1.0)、GBS胰腺炎(P = 0.33)和死亡(0.30)。在择期(P = 0.01)和急诊(P = 0.03)LC中,≥70岁组的CD I-II级并发症高于<70岁组。然而,在急诊LC中,≥70岁组的CD≥3级并发症高于<70岁组(P = 0.01),在择期LC中相当(P = 0.12)。

结论

LC在老年患者中是安全有效的。应加快老年患者的择期LC,以避免急诊入院和急诊LC,因为它们与更高的并发症发生率相关。

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