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颈椎椎板切除术及融合术与颈椎板成形术治疗退行性颈椎脊髓病的倾向评分匹配分析

Cervical laminectomy and fusion versus laminoplasty in degenerative cervical myelopathy: A propensity score matching analysis.

作者信息

Levy Hannon W, Levy Bennett R, Soliman Mohamed A R, Quiceno Esteban, Greisman Jacob David, Khan Asham, Amiotti Juan Bautista, Pollina John, Mullin Jeffrey P

机构信息

School of Medicine and Health Sciences, The George Washington University School of Medicine and Health Sciences, Washington, D.C., United States.

Department of Neurosurgery, New York University School of Medicine, Langone Hospital, New York, United States.

出版信息

Surg Neurol Int. 2025 Jun 6;16:220. doi: 10.25259/SNI_299_2025. eCollection 2025.

Abstract

BACKGROUND

Degenerative cervical myelopathy (DCM) is a common cause of spinal cord dysfunction. The effectiveness of laminoplasty (LP) versus laminectomy with fusion (LF) for treating DCM is still debated. Here, we compared LP versus LF for treating DCM using propensity score matching (PSM) to minimize selection bias.

METHODS

We identified DCM patients undergoing LP versus LF (2004-2022). Our analysis included demographics, preoperative/postoperative modified Japanese orthopedic association (mJOA) scoring, Visual Analog Scale (VAS) scores, assessment of postoperative cervical lordosis, operative time, blood loss, length of stay (LOS), and adverse events. PSM was performed to create balanced groups and minimize selection bias. Paired t-tests and Chi-square tests were used for statistical analysis.

RESULTS

After PSM, 55 patients in each group were analyzed. LP patients had significantly shorter operative times and LOS, but VAS scores were significantly better for the LF group. Notably, both groups showed similar improvements in mJOA scores, frequency of intraoperative/postoperative adverse events, and reoperation rates. Although changes in cervical lordosis were significantly different between the groups, both groups showed comparable final lordotic curvatures.

CONCLUSION

LP procedures resulted in significantly shorter operative times and LOS, but VAS scores were correlated with significantly better outcomes in the LF group. Notably, both LP and LF patients demonstrated similar improvement in mJOA scores, frequencies of intraoperative/postoperative adverse events, and reoperation rates.

摘要

背景

退行性颈椎脊髓病(DCM)是脊髓功能障碍的常见原因。椎板成形术(LP)与椎板切除融合术(LF)治疗DCM的有效性仍存在争议。在此,我们使用倾向评分匹配(PSM)比较LP与LF治疗DCM,以尽量减少选择偏倚。

方法

我们确定了接受LP与LF治疗的DCM患者(2004 - 2022年)。我们的分析包括人口统计学、术前/术后改良日本骨科协会(mJOA)评分、视觉模拟量表(VAS)评分、术后颈椎前凸评估、手术时间、失血量、住院时间(LOS)和不良事件。进行PSM以创建平衡组并尽量减少选择偏倚。采用配对t检验和卡方检验进行统计分析。

结果

PSM后,每组分析55例患者。LP组患者的手术时间和住院时间明显更短,但LF组的VAS评分明显更好。值得注意的是,两组在mJOA评分、术中和术后不良事件发生率以及再次手术率方面均有相似的改善。尽管两组之间颈椎前凸的变化有显著差异,但两组的最终前凸曲率相当。

结论

LP手术的手术时间和住院时间明显更短,但LF组的VAS评分与明显更好的结果相关。值得注意的是,LP组和LF组患者在mJOA评分、术中和术后不良事件发生率以及再次手术率方面均有相似的改善。

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